The last decade or so has seen an increase in the rate of attention to systems change and the application of multiple theories to study and influence change in systems. This article considers how these theories, described in other articles in this issues, plus theories about complex adaptive systems open opportunities for us to continue to expand our repertoire of tools and methods to address systems change. These conceptual frameworks, tools, and methods are expected to help us increase our capacity to study and influence both planned and self-organizing systems change. New tools and methods have emerged and others are needed to help us continue to explore and influence the complex social systems within which we operate.