Table 1

Percentage (number) of guidelines containing the guideline appraisal instrument criteria by category

Guideline appraisal instrument criteriaAll guidelines (N = 52)AHCPR guidelines (N = 17)Updates of AHCPR guidelines (N = 5)Guidelines that reference/adapt AHCPR guidelines (N = 30)
*We added these criteria to the clinical practice guideline appraisal instrument developed by Shaneyfelt et al.
**Since we determined that this criterion was not applicable to the AHCPR guideline on mammography, the total number of guidelines for this criterion was 51 for all of the guidelines and 16 for the AHCPR guidelines.
(1) Purpose of the guideline is specified100 (52)100 (17)100 (5)100 (30)
(2) Rationale and importance of the guideline are explained77 (40)100 (17)100 (5)60 (18)
(3) Participants in the guideline development process and their areas of expertise are specified96 (50)100 (17)80 (4)97 (29)
(3a) Are the participants multidisciplinary?*73 (38)100 (17)40 (2)63 (19)
(4) Targeted health problem or technology is clearly defined100 (52)100 (17)100 (5)100 (30)
(5) Targeted patient population is specified100 (52)100 (17)100 (5)100 (30)
(6) Principal preventive, diagnostic, or therapeutic options available to clinicians and patients are specified100 (51)**100 (16)**100 (5)100 (30)
(7) Method by which the guideline underwent external review is specified58 (30)100 (17)60 (3)33 (10)
(8) Expiration date or date of scheduled review is specified29 (15)12 (2)20 (1)40 (12)
(9) Method for grading or classifying the scientific evidence is specified46 (24)59 (10)40 (2)40 (12)
(10a) Benefits of specific health practices are specified100 (52)100 (17)100 (5)100 (30)
(10b) Harms of specific health practices are specified98 (51)100 (17)80 (4)100 (30)
(11a) Benefits are quantified64 (33)94 (16)100 (5)40 (12)
(11b) Harms are quantified64 (33)94 (16)80 (4)43 (13)
(12) Recommendations are graded according to the strength of evidence46 (24)82 (14)40 (2)27 (8)
(12a) Is there a definition for the strength of evidence they use?*46 (24)82 (14)40 (2)27 (8)
(13) Effect on health care costs from specific health practices is specified44 (23)94 (16)20 (1)20 (6)
(14) Costs are quantified37 (19)82 (14)20 (1)13 (4)
(15) Role of patient preferences is discussed60 (31)82 (14)40 (2)50 (15)
(16) Health outcomes are specified100 (52)100 (17)100 (5)100 (30)
(17) Flexibility in the recommendations is specified87 (45)100 (17)40 (2)87 (26)
(18) Evidence used is identified by citation and referenced92 (48)100 (17)100 (5)87 (26)
(19) Formal methods of combining evidence or expert opinion are used and described2 (1)0 (0)0 (0)3 (1)
(20) Recommendations are specific and apply to the stated goals of the guideline98 (51)94 (16)100 (5)100 (30)
(21) Role of value judgements used by the guideline developers in making recommendations is discussed14 (7)6 (1)0 (0)20 (6)
(22) Intended audience or users of the guideline are specified83 (43)94 (16)80 (4)77 (23)
(23) Method of identifying evidence is specified54 (28)100 (17)60 (3)27 (8)
(23a) Was there a systematic review of the evidence?*52 (27)100 (17)60 (3)23 (7)
(24) Time period from which evidence is reviewed is specified39 (20)47 (8)60 (3)30 (9)
(25) Method of data extraction is specified21 (11)47 (8)20 (1)7 (2)