Table 3

Drug classes most frequently associated with preventable drug related admission due to prescribing problems

British National Formulary classAdverse drug eventPrescribing problemNumber of cases
*If a drug related admission involves more than one causative drug it may be recorded more than once in the table.
†Further details on “other” drug categories are available on the QSHC website (www.qshc.com/supplemtal).
Non-steroidal anti-inflammatory drugsGastrointestinal toxicityPrescription in patients with two or more risk factors without gastrointestinal prophylaxis*21
Renal tubular necrosisConcurrent prescription of two full dose non-steroidal anti-inflammatory drugs without monitoring renal function1
Subtotal22
Antiplatelet drugsGastrointestinal toxicityPrescription in patients with two or more risk factors without gastrointestinal prophylaxis*13
Thrombotic eventFailure to prescribe in patients needing secondary prevention4
Subtotal17
Beta-adrenoceptor blocking drugsCongestive cardiac failurePrescription of standard dose beta-blocker in patient with known congestive cardiac failure2
Co-prescription of atenolol with verapamil*1
TachycardiaSudden cessation1
Bleeding oesophageal varicesCessation without prescription of alternative1
Chest painFailure to maximise anti-anginal therapy despite ongoing symptoms over a period of time*2
Subtotal7
AntiepilepticsFittingSubtherapeutic prescription4
Inappropriate cessation2
Subtotal6
Other38†