Table 3

 Prescribing error results summary

CitationNumerator and numerator descriptionDenominator and denominator description
ADE, adverse drug event; CPOE, computerised physician order entry; MAR, medication administration record; PICU, paediatric intensive care unit; PRN, drug administered as required; TPN, total parenteral nutrition; VLBW, very low birth weight.
*Potential ADE defined as having the potential to produce significant injury, includes errors detected before drug administration as well as errors that did not produce significant adverse consequences, excludes errors that were identified and corrected before the drug was entered into MAR.
France et al2471 Chemotherapy ordering errors: includes dosing, omission and wrong date errors97 Electronically reported chemotherapy errors in 13 months
Lehmann et al2760 TPN errors that required pharmacist to contact provider: includes osmolality problems, insufficient fluid, calculation errors, omissions557 TPN orders in 1.5 months
Cordero et al2914 Gentamicin prescription dosage errors: prescribed dose >10% deviation from recommended dose 5 Gentamicin overdoses: >10% overdose 9 Gentamicin underdoses: >10% underdose105 VLBW infants born consecutively 6 months before CPOE receiving drug
Potts et al302049 Medication prescribing errors: includes weight not available, missing information6803 Manual PICU orders in 2 months
Sangtawesin et al31114 Prescribing errors: includes wrong dose, wrong choice, known allergy and others32105 Admissions in 14 months
King et al3313 Prescribing medication errors416 Medication errors in 3 years
Fontan et al34937 Prescribing errors: includes any error in the prescription of drug’s name, form, dosage, route, any omission of these prescribing items including prescriber’s name and any drug interaction.4532 Prescribed drugs in 2 months
419 Computerised prescribing errors as defined above3943 Computerised prescribed drugs in 2 months
518 Hand written prescribing errors589 Hand written prescribed drugs in 2 months
44 Wrong form errors 19 Wrong route errors 47 Wrong dosage errors 34 Wrong dosage form errors 587 Omission errors 152 “Caution” drug interactions 0 “Contraindicated” and “not advised” drug interactions4532 Prescribed drugs in 2 months
Holdsworth et al3535 Preventable ADEs that were underdose, wrong dose and overdose: preventable was determined by authors46 Preventable ADEs in 8 months
39 Potential ADEs* that were underdose and overdose94 Potential ADEs* in 8 months as defined above
Lesar3639 Prescribing errors occurring in paediatric patients: all errors were prevented before reaching patient200 Error reports identified by pharmacists and entered into a relational database in 6 months
0.53 10-Fold error rate in paediatric patientsPer 100 admissions, recorded over 6 months
0.98 10-Fold error rate in paediatric patientsPer 1000 patient days, recorded over 6 months
Frey et al38102 Overall prescribing errors 9 Illegible errors 37 Calculation errors 22 Wrong unit errors (eg ml instead of mg)275 Error reports in 2001
Kozer et al39154 Prescribing errors 117 Wrong frequency errors 133 Wrong dose errors 5 Wrong drug errors 7 Wrong route errors1532 Charts reviewed in 12 randomly selected days in summer
Pichon et al4076 Incomplete non-chemotherapy orders defined as omissions: number of doses missing, route missing, dose missing 89 Non-chemotherapy order omissions: more than one omission possible in a single order198 Non-chemotherapy orders
19 Omissions on non-chemotherapy PRN¥ orders22 Non-chemotherapy PRN¥ orders
Kaushal et al42454 Physician ordering medication errors 91 Physician ordering potential ADEs*: defined as errors with significant potential for injuring patient10 778 Orders, 1120 admissions and 3932 patient days in 6 weeks
Farrar et al4929 Prescribing errors for non-paediatricians for orders reviewed38 Non-paediatricians’ orders reviewed
17 Prescribing errors for paediatricians for orders reviewed65 Paediatricians’ orders reviewed