Table 2

Adverse drug events (ADEs)

Triggers (n)Unique episodes (n)ADEs (n)Proportion triggers that were ADEs (95% CI)StageEffect on patient
INR >58548460.96 (0.90 to 1)

  • 0 Prescribing

  • 0 Dispensing

  • 0 Self-administration

  • 46 Monitoring

  • 0 None

  • 35 Minimal

  • 8 Mild

  • 3 Moderate

  • 0 Severe

  • 0 NA

BUN >60 mg/dl618103120.12 (0.06 to 0.18)

  • 0 Prescribing

  • 0 Dispensing

  • 12 Self-administration

  • 0 Monitoring

  • 0 None

  • 7 Minimal

  • 4 Mild

  • 0 Moderate

  • 1 Severe

  • 0 NA

ALT >84 lU/l644205190.09 (0.07 to 0.11)

  • 0 Prescribing

  • 0 Dispensing

  • 16 Self-administration

  • 2 Monitoring

  • 1 NA

  • 0 None

  • 16 Minimal

  • 0 Mild

  • 1 Moderate

  • 1 Severe

  • 1 NA

Creatinine >2.5 mg/dl123862100.08 (0.06 to 0.10)

  • 0 Prescribing

  • 0 Dispensing

  • 10 Self Administration

  • 0 Monitoring

  • 0 None

  • 4 Minimal

  • 5 Mild

  • 0 Moderate

  • 1 Severe

  • 0 NA

AST >80 IU/I45314340.03 (0.00 to 0.06)

  • 0 Prescribing

  • 0 Dispensing

  • 3 Self-administration

  • 1 Monitoring

  • 0 None

  • 3 Minimal

  • 0 Mild

  • 1 Moderate

  • 0 Severe

  • 0 NA

Total1342622910.15 (0.12 to 0.18)

  • 0 Prescribing

  • 0 Dispensing

  • 41 Self-administration

  • 49 Monitoring

  • 1 NA

  • 0 None

  • 65 Minimal

  • 17 Mild

  • 5 Moderate

  • 3 Severe

  • 1 NA

  • ALT, alanine aminotransferase; AST, aspartate aminotransferase; BUN, blood urea nitrogen; INR, international normalised ratio.