Table 2

‘Typical’ EQ5D states associated with adverse events in each severity class, as defined by Brennan et al24

Health state	Example: Warfarin complication	Mobility	Self-care	Usual activities	Pain/discomfort	Anxiety/depression	Index	Utility	Disutility
Moderate Impairment, recovery 1–6 months	Readmission for minor bleeding	1	1	2	1	1	11211	0.88	0.12
Moderate Impairment, recovery >6 months	Major Gastrointestinal bleeding	2	1	2	1	1	21211	0.81	0.19
Permanent Impairment	Stroke, leaving residual moderate hemiplegia	2	2	2	1	2	22212	0.64	0.36
Permanent—Severe	Stroke, leaving dense hemiplegia	2	2	3	1	2	22312	0.31	0.69

For each dimension 1 represents no handicap, 2 represents a moderate handicap, and #3 represents a severe handicap.