Table 1

Results of 2-level Mixed-effects Logistic Regression and population-average estimates for HAPU incidence by patient-encounter.

	2-Level Mixed-effects Logitistic Regression				Population-average Estimates (GEE)
Variable	Estimate	Odds Ratio	Standard Error	P-value	Estimate	Odds Ratio	Standard Error	P-value
Intercept	−9.469	0.000	0.331	<0.001	−7.016	0.001	0.175	<0.001
Age	0.049	1.050	0.003	<0.001	0.040	1.041	0.002	<0.001
Bronchoscopy	0.513	1.671	0.248	0.038	0.408	1.504	0.190	0.032
Culture, Stool	0.514	1.672	0.158	0.001	0.414	1.512	0.123	0.001
Urinalysis Chemistry Screen	0.841	2.319	0.089	<0.001	0.693	2.000	0.073	<0.001
Pre-albumin	0.983	2.674	0.091	<0.001	0.761	2.141	0.067	<0.001
Vancomycin Random Assay	0.959	2.609	0.094	<0.001	0.728	2.071	0.069	<0.001
Culture & Stain, Wound Drainage	0.790	2.203	0.135	<0.001	0.582	1.790	0.098	<0.001
Topical Sulfonamides	1.732	5.653	0.115	<0.001	1.297	3.660	0.078	<0.001
Topical/Mucous Membrane/Subcutaneous Enzymes	3.389	29.622	0.276	<0.001	2.109	8.236	0.167	<0.001
Phosphate Replacement	0.260	1.297	0.085	0.002	0.204	1.227	0.068	0.003
Antifu ngal Agent	0.472	1.603	0.094	<0.001	0.385	1.470	0.075	<0.001
Erythropoiesis-stimulating Agent	0.995	2.705	0.134	<0.001	0.768	2.156	0.098	<0.001
ICD-9 V49.84: Bed Confinement	3.457	31.730	0.539	<0.001	2.198	9.003	0.334	<0.001
ICD-9 907.2: Spinal Cord Injury	5.511	247.364	0.500	<0.001	3.814	45.311	0.318	<0.001
ICD-9 730.15: Chronic Osteomyelitis – Pelvic a nd Thigh Regions	3.323	27.746	0.697	<0.001	2.312	10.094	0.474	<0.001
ICD-9 730.18: Chronic Osteomyelitis – Other	3.001	20.099	0.806	<0.001	1.932	6.904	0.516	<0.001
Variance(lntercept)	4.355		0.486
Log-likelihood	−4737.36