Primary outcome measures
| Outcome | Prevalence | Goodness of fit (Hosmer & Lemeshow test, Nagelkerke's R2) | Unadjusted OR, 95% CI | Adjusted OR accounting for clustering, 95% CI | |
|---|---|---|---|---|---|
| Standard, n (%) | Intervention, n (%) | ||||
| Admission error, per patient | 49/121 (40.5) | 10/112 (9.0) | 0.737, 0.239 | 0.15, 0.07 to 0.30 | *0.14, 0.07 to 0.31 |
| Discharge error, per patient | 66/101 (65.3) | 15/108 (13.9) | 0.723, 0.418 | 0.09, 0.04 to 0.17 | †0.07, 0.03 to 0.15 |
| Extreme sensitivity analysis Missing data treated as error present | 86/121 (71.1) | 19/112 (17.0) | 0.406, 0.415 | 0.08, 0.04 to 0.16 | †0.07, 0.04 to 0.14 |
| Missing data treated as error not present | 66/121 (54.5) | 15/112 (13.4) | 0.759, 0.306 | 0.13, 0.07 to 0.25 | †0.11, 0.06 to 0.23 |
| Discharge: potential to cause harm‡, n (%) | |||||
| No error, no harm (VAS score 0) | 35 (34.7) | 93 (86.1) | |||
| Minor harm (VAS score <3) | 6 (5.9) | 2 (1.9) | |||
| Moderate harm (VAS score 3–7) | 54 (53.5) | 13 (12.0) | |||
| Severe harm (VAS score >7) | 6 (5.9) | 0 (0) | |||
| VAS score for potential harm‡ (median, IQR) | 4 (0 to 5) | 0 (0 to 0) | Mann–Whitney U p 0.000 | ||
*Multilevel logistic regression, adjusted for Charlson comorbidity index, number of medicines (relates to the total number of medications prescribed before admission and those added during admission that remained active at discharge, exclusive of medications commenced and stopped within the hospital episode), age.
†Multilevel logistic regression, adjusted for Charlson comorbidity index, number of medicines (relates to the total number of medications prescribed before admission and those added during admission that remained active at discharge, exclusive of medications commenced and stopped within the hospital episode), age, length of stay.
‡Calculated across all 209 patients for whom the primary outcome measure was available, with a value of 0 applied for no error.
VAS, visual analogue score.