Weighted occurrence of Irish National Adverse Events Study (INAES) adverse events with the application of international adverse event eligibility criteria
| Adverse event eligibility criteria | Weighted prevalence (95% CI) | Weighted incidence density (95% CI) | Magnitude (%) change in prevalence |
|---|---|---|---|
| Include only events related to the index hospital (exclude events caused by healthcare management outside the index hospital) with healthcare management causation at least more likely (≥4 out of 6, online supplementary appendix 2). INAES prevalence | 12.2% (9.5% to 15.5%) | N/A* | Baseline |
| Exclude adverse events detected after the index admission | 9.4% (7.4% to 11.9%) | 10.9 events per 100 admissions (8.2 to 13.7) | 23% decrease |
| Exclude adverse events occurring prior to the index admission. INAES incidence | 8.6% (6.7% to 10.9%) | 10.3 events per 100 admissions (7.5 to 13.1) | 30% decrease |
| Include adverse events in all settings (ie, include events caused by healthcare management outside the index hospital) | 14.6% (11.6% to 18.3%) | N/A* | 20% increase |
| Include events with at least slight-to-moderate evidence for healthcare management causation (≥2 out of 6, online supplementary appendix 2) | 14.5% (11.3% to 18.4%) | N/A* | 19% increase |
| Include all events with at least slight-to-moderate evidence for healthcare management causation (≥2 out of 6, online supplementary appendix 2) in all settings | 17.0% (13.4% to 21.3%) | N/A* | 39% increase |
*Not applicable: unable to calculate an incidence because including events occurring in admissions prior to the index admission as well as events detected in subsequent admissions will result in double counting.