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Cited by (178)
Placebo and Active Treatment Additivity in Placebo Analgesia: Research to Date and Future Directions
2018, International Review of NeurobiologyA qualitative exploration of how patients conceptualise their acupuncturists: Technicians, caring professionals, and wise healers
2016, Complementary Therapies in MedicineCitation Excerpt :We have previously described in detail our epistemology (critical realist) and analytic approach.39 In brief, we began by using techniques from framework analysis42 to organise patients’ talk into five domains of contextual features: themselves in relation to acupuncture, acupuncture consultations and treatments, their acupuncturist, their relationship with their acupuncturist, and the physical and institutional setting of acupuncture.14,43 The findings reported below emerged from an inductive thematic analysis44,45 of patients’ talk about their acupuncturist.
Using a matrix-analytical approach to synthesizing evidence solved incompatibility problem in the hierarchy of evidence
2015, Journal of Clinical EpidemiologyCitation Excerpt :It uses a subtractive rationale: By comparing a true treatment group to a sham group, it factually subtracts the effect of the true treatment from those of the control treatment and only looks at the difference, neglecting everything else [10,38]. This procedure makes a vital assumption that has rarely been tested and if tested has been found to be wrong [39]: Namely that the treatment components are additive and that the nonspecific effects are roughly stable and uncorrelated with treatment effects across trials. The latter assumption has been shown to be wrong: Treatment and placebo effects are highly correlated at r = 0.78 in a variety of studies with treatment duration of more than 3 months [40].
Placebo Studies (Double-Blind Studies)
2015, International Encyclopedia of the Social & Behavioral Sciences: Second EditionEffect of variability in the 7-day baseline pain diary on the assay sensitivity of neuropathic pain randomized clinical trials: An ACTTION study
2014, PainCitation Excerpt :Physiologically this could occur if there is an overlap in some component of the pain reduction pathways for the mind– body effect and the specific effect of the active medication. In this subadditive state [1,13,26,27], the overall group response and ratio of placebo to active medication group responses can change based on the degree of overlap (Fig. 4b). If there is also a maximal total benefit possible from the active medication treatment, the differences between groups would be as diagrammed in Fig. 4c.
Placebo Effects in Complementary and Alternative Medicine. The Self-Healing Response.
2013, Placebo and Pain: From Bench to Bedside