User profiles for "author:D Bell"

Derek Bell

Imperial College London
Verified email at imperial.ac.uk
Cited by 21841

Epidermal growth factor receptor mutations in lung cancer

SV Sharma, DW Bell, J Settleman, DA Haber - Nature Reviews Cancer, 2007 - nature.com
The development and clinical application of inhibitors that target the epidermal growth factor
receptor (EGFR) provide important insights for new lung cancer therapies, as well as for the …

Vitamin D deficiency: an important, common, and easily treatable cardiovascular risk factor?

JH Lee, JH O'Keefe, D Bell, DD Hensrud… - Journal of the American …, 2008 - jacc.org
Vitamin D deficiency is a highly prevalent condition, present in approximately 30% to 50% of
the general population. A growing body of data suggests that low 25-hydroxyvitamin D …

Myalgic encephalomyelitis: international consensus criteria

BM Carruthers, MI van de Sande… - Journal of internal …, 2011 - Wiley Online Library
Carruthers BM, van de Sande MI, De Meirleir KL, Klimas NG, Broderick G, Mitchell T, Staines
D, Powles ACP, Speight N, Vallings R, Bateman L, Baumgarten‐Austrheim B, Bell DS, Carlo …

[HTML][HTML] Activating mutations in the epidermal growth factor receptor underlying responsiveness of non–small-cell lung cancer to gefitinib

TJ Lynch, DW Bell, R Sordella… - … England Journal of …, 2004 - Mass Medical Soc
Background Most patients with non–small-cell lung cancer have no response to the tyrosine
kinase inhibitor gefitinib, which targets the epidermal growth factor receptor (EGFR) …

[HTML][HTML] DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

M Okano, DW Bell, DA Haber, E Li - Cell, 1999 - cell.com
The establishment of DNA methylation patterns requires de novo methylation that occurs
predominantly during early development and gametogenesis in mice. Here we demonstrate …

Isolation of rare circulating tumour cells in cancer patients by microchip technology

S Nagrath, LV Sequist, S Maheswaran, DW Bell… - Nature, 2007 - nature.com
Viable tumour-derived epithelial cells (circulating tumour cells or CTCs) have been identified
in peripheral blood from cancer patients and are probably the origin of intractable metastatic …

[HTML][HTML] Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study

…, M Beadsworth, P Beirne, R Bell, D Bell… - The Lancet …, 2021 - thelancet.com
Background The impact of COVID-19 on physical and mental health and employment after
hospitalisation with acute disease is not well understood. The aim of this study was to …

Brown v. Board of Education and the interest-convergence dilemma

DA Bell Jr - Harvard law review, 1980 - JSTOR
After Brown v. Board of Education was decided, Professor Herbert Wechsler questioned
whether the Supreme Court's decision could be justified on the basis of" neutral" principles …

[HTML][HTML] Trial of early, goal-directed resuscitation for septic shock

…, RD Grieve, R Jahan, SE Harvey, D Bell… - … England Journal of …, 2015 - Mass Medical Soc
Background Early, goal-directed therapy (EGDT) is recommended in international
guidelines for the resuscitation of patients presenting with early septic shock. However …

[HTML][HTML] Detection of Mutations in EGFR in Circulating Lung-Cancer Cells

S Maheswaran, LV Sequist, S Nagrath… - … England Journal of …, 2008 - Mass Medical Soc
Background The use of tyrosine kinase inhibitors to target the epidermal growth factor
receptor gene (EGFR) in patients with non–small-cell lung cancer is effective but limited by …