PURPOSE: Subclinical hypothyroidism has been associated with elevated cholesterol and
increased risk for atherosclerosis, but data on the risk of coronary heart disease (CHD) are …

Background Controversy exists regarding the usefulness of troponin testing for the risk
stratification of patients with acute pulmonary embolism (PE). We conducted an updated …

Importance The benefit of thyroid hormone therapy for subclinical hypothyroidism is
uncertain. New evidence from recent large randomized clinical trials warrants an update of …

Background: Diagnosis of pulmonary embolism requires clinical probability assessment.
Implicit assessment is accurate but is not standardized, and current prediction rules have …

Rationale: An objective and simple prognostic model for patients with pulmonary embolism
could be helpful in guiding initial intensity of treatment. Objectives: To develop a clinical …

Background The Pulmonary Embolism Severity Index (PESI) estimates the risk of 30-day
mortality in patients with acute pulmonary embolism (PE). We constructed a simplified …

Background Although practice guidelines recommend outpatient care for selected,
haemodynamically stable patients with pulmonary embolism, most treatment is presently …

Background Guidelines recommend the use of nutritional support during hospital stays for
medical patients (patients not critically ill and not undergoing surgical procedures) at risk of …

Importance Because effective interventions to reduce hospital readmissions are often
expensive to implement, a score to predict potentially avoidable readmissions may help …

Background—American College of Cardiology/American Heart Association guidelines for
the diagnosis and management of heart failure recommend investigating exacerbating …