User profiles for "author:P Hudson"
 | Peter HudsonPenn State University Verified email at psu.edu Cited by 33433 |
Engineered antibody fragments and the rise of single domains
P Holliger, PJ Hudson - Nature biotechnology, 2005 - nature.com
With 18 monoclonal antibody (mAb) products currently on the market and more than 100 in
clinical trials, it is clear that engineered antibodies have come of age as biopharmaceuticals …
clinical trials, it is clear that engineered antibodies have come of age as biopharmaceuticals …
[HTML][HTML] Impacts of biodiversity on the emergence and transmission of infectious diseases
Current unprecedented declines in biodiversity reduce the ability of ecological communities
to provide many fundamental ecosystem services. Here we evaluate evidence that reduced …
to provide many fundamental ecosystem services. Here we evaluate evidence that reduced …
Seasonality and the dynamics of infectious diseases
Seasonal variations in temperature, rainfall and resource availability are ubiquitous and can
exert strong pressures on population dynamics. Infectious diseases provide some of the best …
exert strong pressures on population dynamics. Infectious diseases provide some of the best …
A parathyroid hormone-related protein implicated in malignant hypercalcemia: cloning and expression
LJ Suva, GA Winslow, REH Wettenhall, RG Hammonds… - Science, 1987 - science.org
Humoral hypercalcemia of malignancy is a common complication of lung and certain other
cancers. The hypercalcemia results from the actions of tumor factors on bone and kidney …
cancers. The hypercalcemia results from the actions of tumor factors on bone and kidney …
Is a healthy ecosystem one that is rich in parasites?
Historically, the role of parasites in ecosystem functioning has been considered trivial
because a cursory examination reveals that their relative biomass is low compared with that …
because a cursory examination reveals that their relative biomass is low compared with that …
Multi-subunit proteins on the surface of filamentous phage: methodologies for displaying antibody (Fab) heavy and light chains
…, KS Johnson, DJ Chiswell, P Hudson… - Nucleic acids …, 1991 - academic.oup.com
The display of proteins on the surface of phage offers a powerful means of selecting for rare
genes encoding proteins with binding activities. Recently we found that antibody heavy and …
genes encoding proteins with binding activities. Recently we found that antibody heavy and …
Prevention of population cycles by parasite removal
The regular cyclic fluctuations in vertebrate numbers have intrigued scientists for more than
70 years, and yet the cause of such cycles has not been clearly demonstrated. Red grouse …
70 years, and yet the cause of such cycles has not been clearly demonstrated. Red grouse …
Parathyroid hormone-related protein purified from a human lung cancer cell line.
JM Moseley, M Kubota… - Proceedings of the …, 1987 - National Acad Sciences
A protein with biological activities similar to parathyroid hormone (PTH) has been purified
from serum-free culture medium obtained from a human lung cancer cell line (BEN). A major …
from serum-free culture medium obtained from a human lung cancer cell line (BEN). A major …
A multi-species synthesis of physiological mechanisms in drought-induced tree mortality
HD Adams, MJB Zeppel, WRL Anderegg… - Nature ecology & …, 2017 - nature.com
Widespread tree mortality associated with drought has been observed on all forested
continents and global change is expected to exacerbate vegetation vulnerability. Forest …
continents and global change is expected to exacerbate vegetation vulnerability. Forest …
[BOOK][B] The ecology of wildlife diseases
The majority of living organisms are parasitic in one form or another, be they a virus invading
a sea coral, a tapeworm within the guts of your dog, a cuckoo chick in a reed warbler's nest …
a sea coral, a tapeworm within the guts of your dog, a cuckoo chick in a reed warbler's nest …