Hypoxia is known to act as a general stimulator of cells derived from marrow precursors. We
investigated the effect of oxygen tension on the formation and function of osteoclasts, the …

Background Inappropriate attendances may account for up to 40% of presentations at
accident and emergency (A&E) departments. There is considerable interest from health …

Aim Desmoid tumours (DT) are myofibroblastic proliferations occurring in 15% of patients with
familial adenomatous polyposis (FAP). Several small series have analysed the incidence …

Background The annual number of unplanned attendances at accident and emergency (A&E)
departments in England increased by 11% (2.2 million attendances) between 2008–2009 …

Introduction Sotrovimab, a recombinant human monoclonal antibody (mAb) against severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) had US Food and Drug …

A service evaluation of Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) testing
and result notification in patients attending a rapid testing service (Dean Street Express […

Background The minimum age for the legal purchase of tobacco increased from 16 to 18 years
in England, Scotland and Wales on 1 October 2007. The authors examined the impact of …

Purpose To evaluate clinical outcomes associated with sotrovimab use during Omicron BA.2
and BA.5 predominance. Methods Electronic databases were searched for observational …

Primary care is a major component of England's National Health Service (NHS), responsible
for approximately 300 million consultations per year with GPs in England, which represents …

Introduction There is limited real-world evidence surrounding the effectiveness of early, mild-to-moderate
COVID-19 treatments following the emergence and dominance of Omicron …