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032 Rapid Guidelines: A Systematic Review
  1. M Falavigna1,2,3,
  2. I Ikobaltzeta4,
  3. F Sakhia3,
  4. Y Zhang3,
  5. N Santesso3,
  6. S Norris5,
  7. H Schünemann3,6
  1. 1Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
  2. 2IATS - National Institute of Science and Technology for HTA, Porto Alegre, Brazil
  3. 3Department of Clinical Epidemiology and Biostatistics. McMaster University, Hamilton, Canada
  4. 4OSTEBA - Basque Office for Health Technology Assessment, Vitoria-Gasteiz, Spain
  5. 5World Health Organization, Geneve, Switzerland Department of Medicine
  6. 6McMaster University Hamilton, Canada


Background Guidelines often take two or more years to be developed. This timeframe is not practical for providing guidance in situations when rapid advice is needed.

Objectives To describe current practices about the development of rapid guidelines and to provide advice about adequate methodology.

Methods We performed a systematic review, including grey literature, to identify (1) rapid guidelines, defined as guidelines produced in a shortened time frame, and (2) methodological manuals addressing its development.

Results We only documents by WHO and NICE that described methods and actual guidelines. The WHO handbook describes “rapid advice guidelines”; guidelines produced in response to a public health emergency in which WHO is required to provide rapid global leadership and guidance. This advice should be produced within 1 to 3 months and be evidence-informed, however, it may not be supported by full reviews of the evidence. We identified six WHO rapid guidelines and one methodological guidance paper based on a WHO guideline. NICE produces “short clinical guidelines”; guidelines that address only part of a care pathway, allowing rapid (11–13-month) development of guidance on aspects of care for which the NHS requires urgent advice. We identified 18 NICE short clinical guidelines.

Discussion Literature is lacking about rapid guidelines and the intended role appears to differ. Despite its relevance, there are few rapid guidelines published and clarity about the terminology is needed.

Implications for Guideline Developers We will provide a framework for those developing rapid guidelines, including practical advice and clarification about the terminology used.

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