RT Journal Article SR Electronic T1 Systematic reviews of the effectiveness of quality improvement strategies and programmes JF Quality and Safety in Health Care JO Qual Saf Health Care FD BMJ Publishing Group Ltd SP 298 OP 303 DO 10.1136/qhc.12.4.298 VO 12 IS 4 A1 J Grimshaw A1 L M McAuley A1 L A Bero A1 R Grilli A1 A D Oxman A1 C Ramsay A1 L Vale A1 M Zwarenstein YR 2003 UL http://qualitysafety.bmj.com/content/12/4/298.abstract AB Systematic reviews provide the best evidence on the effectiveness of healthcare interventions including quality improvement strategies. The methods of systematic review of individual patient randomised trials of healthcare interventions are well developed. We discuss methodological and practice issues that need to be considered when undertaking systematic reviews of quality improvement strategies including developing a review protocol, identifying and screening evidence sources, quality assessment and data abstraction, analytical methods, reporting systematic reviews, and appraising systematic reviews. This paper builds on our experiences within the Cochrane Effective Practice and Organisation of Care (EPOC) review group.