RT Journal Article
SR Electronic
T1 The quest to eliminate intrathecal vincristine errors: a 40-year journey
JF Quality and Safety in Health Care
JO Qual Saf Health Care
FD BMJ Publishing Group Ltd
SP 323
OP 326
DO 10.1136/qshc.2008.030874
VO 19
IS 4
A1 Douglas J Noble
A1 Liam J Donaldson
YR 2010
UL http://qualitysafety.bmj.com/content/19/4/323.abstract
AB Background Intrathecal administration of vincristine is a rare event but catastrophic for the patient, family and clinical team involved. Analysis of this source of harm shows it to be a classic systems error which has proved intractable for nearly 40 years. Failure to learn from history, communicate safety solutions nationally and internationally, create safety agencies which effectively and reliably prevent adverse events, conduct investigations and enquiries which fully reveals how to mitigate system error, develop robust physical design solutions to prevent harm to patients, make effective solutions universal and preparing for the unexpected are all major challenges.Conclusions The elimination of rare yet catastrophic errors like this remains one of the tests of whether we can make healthcare safer. In this paper, we discuss why effective learning has been so slow and illustrate lessons for other fields of patient safety.