RT Journal Article SR Electronic T1 Anaesthetic drug administration as a potential contributor to healthcare-associated infections: a prospective simulation-based evaluation of aseptic techniques in the administration of anaesthetic drugs JF BMJ Quality & Safety JO BMJ Qual Saf FD BMJ Publishing Group Ltd SP 826 OP 834 DO 10.1136/bmjqs-2012-000814 VO 21 IS 10 A1 Derryn A Gargiulo A1 Janie Sheridan A1 Craig S Webster A1 Simon Swift A1 Jane Torrie A1 Jennifer Weller A1 Kaylene Henderson A1 Jacqueline Hannam A1 Alan F Merry YR 2012 UL http://qualitysafety.bmj.com/content/21/10/826.abstract AB Objective To evaluate the possibility that anaesthetists are administering potentially pathogenic micro-organisms to their patients. Design Prospective microbiological and observational study in a realistic simulated setting. Participants Ten anaesthetists supported by 10 anaesthetic technicians. Primary outcome measure The presence or absence of organisms cultured from sterile intravenous bags used to collect drugs injected during the simulated cases and from the needles and the contents of the syringes used. The authors also observed the aseptic techniques used. Results Organisms were isolated from five of 38 (13%) bags from five of 20 simulated cases anaesthetised by four of 10 anaesthetists, 10 of 197 (5%) syringes and six of 17 (35%) needles. None of the anaesthetists washed their hands prior to entry, used the hand gel provided, disinfected the phial septa before drawing up drugs or disinfected the intravenous ports on the intravenous administration set before use. One was seen to recap a needle left on a syringe for possible reuse. Three participants were observed to place equipment such as stethoscopes, drug charts and pens on top of their inuse drug trays. Conclusion The administration of intravenous drugs during anaesthesia may be an important factor in the genesis (or potentially the prevention) of healthcare-associated infection. These observations suggest room for improvement in the aseptic techniques of at least some anaesthetists when preparing and administering intravenous drugs. Confirmation of these findings in clinical settings is needed. Study registry number (for the VASER study) Australian New Zealand Clinical Trials Registry: Ref: ACTRN 12609000530224, https://www.anzctr.org.au/registry/trial_review.aspx?ID=308128; note that the work presented here is a subset of the registered trial and its outcomes were not included in this registration.