Table 1

Domain structure for guideline quality obtained from principal components analysis, mean (SD) values of domain scores, and percentage of variance explained by each domain (item numbers represent the order in the instrument)

*Coefficients from varimax rotated factor matrix.
Domain 1: Scope and purpose
Mean percentage domain score = 69.3; SD = 21.3; range 16.7–97.2; % variance = 4.6
1. The overall objective(s) of the guideline is (are) specifically described0.594
2. The clinical question(s) covered by the guideline is (are) specifically described0.768
3. The patients to whom the guideline is meant to apply are specifically described0.702
Domain 2: Stakeholder involvement
Mean percentage domain score = 36.1; SD = 18.9; range 4.2–68.7; % variance = 6.6
4. The guideline development group includes individuals from all the relevant professional groups0.643
5. The patients’ views and preferences have been sought0.580
6. The target users of the guideline are clearly defined0.683
7. The guideline has been piloted among end users0.471
Domain 3: Rigour of development
Mean percentage domain score = 40.7; SD = 25.0; range 0–89.3; % variance = 42.3
8. The systematic methods were used to search for evidence0.794
9. The criteria for selecting the evidence are clearly described0.763
10. The methods used for formulating the recommendations are clearly described0.750
11. The health benefits, side effects and risks have been considered in formulating the recommendations0.689
12. There is an explicit link between the recommendations and the supporting evidence0.753
13. The guideline has been externally reviewed by experts prior to its publication0.589
14. A procedure for updating the guideline is provided0.619
Domain 4: Clarity and presentation
Mean percentage domain score = 65.8; SD = 14.1; range 37.5–91.7; % variance = 8.6
15. The recommendations are specific and unambiguous0.716
16. The different options for management of the condition are clearly presented0.589
17. Key recommendations are easily identifiable0.739
18. The guideline is supported with tools for application0.640
Domain 5: Applicability
Mean percentage domain score = 36.9; SD = 23.2; range 0–91.7; % variance = 6.1
19. The potential organisational barriers in applying the recommendations have been discussed0.804
20. The potential cost implications of applying the recommendations have been considered0.697
21. The guideline presents key review criteria for monitoring and/or audit purposes0.684
Domain 6: Editorial independence
Mean percentage domain score 30.3; SD = 22.4; range 0–72.2
22. The guideline is editorially independent from the funding body
23. Conflicts of interest of guideline development members have been recordedNew item