Table 1

Studies and data sources for target diagnoses

Target diagnosis	Patients	Setting	Clinically detected cases	Clinically missed cases detected at necropsy
*Tuberculosis first detected after death were those cases identified at necropsy or using antemortem cultures that became positive after death in patients receiving fewer than two anti-tuberculosis medications during the last 24 hours of life, as defined in other epidemiological studies.⁴⁶
Aortic dissection⁴⁰	Patients admitted through emergency department and diagnosed with aortic dissection at any point during hospitalization or at necropsy	Three hospitals affiliated with University of Pittsburgh; 1992–6	37	6
Aortic dissection⁴¹	Patients diagnosed at any point during hospitalization or at necropsy	Henry Ford Health System, Detroit; 1985–94	77	6
Pulmonary embolism⁴²	International registry of patients with suspected or confirmed pulmonary embolism	52 teaching hospitals in seven countries; 1995–6	2393	61
Active tuberculosis⁴³	Cases of active tuberculosis, including those diagnosed after death*, reported to a regional department of public health	San Francisco; 1986–95	2982	120*