Failure modes and comparative criticality indexes (CIs) for the old and new processes
| Process steps | Failure modes | Criticality index | Reduction factor(new/old) | |
|---|---|---|---|---|
| Old process | New process | |||
| Prescription | Typing error | 105 | 28 | 3.8 |
| Dosage determination error | 175 | 28 | 6.3 | |
| Programme unavailability | 9 | 20 | 0.5 | |
| Prescription of a solution impossible to produce | 18 | 5 | 3.6 | |
| Transmission to pharmacy | Readability problems | 210 | 7 | 30.0 |
| Transmission to wrong destination | 45 | 9 | 5.0 | |
| Pharmaceutical validation | Failure to detect a typing error during prescription | 175 | 175 | 1.0 |
| Failure to detect a dosage error | 210 | 105 | 2.0 | |
| Label production | Re-transcription error | 72 | 2 | 36.0 |
| Poor printing quality | 10 | 4 | 2.5 | |
| Compounding | Product exchange | 384 | 48 | 8.0 |
| Product omission | 336 | 112 | 3.0 | |
| Dosage error | 512 | 64 | 8.0 | |
| Microbial contamination | 189 | 126 | 1.5 | |
| Chemical cross-contamination | 210 | 21 | 10.0 | |
| Labelling error | 315 | 315 | 1.0 | |
| Quality control | Failure to detect a dosage/product error | 360 | 288 | 1.3 |
| Failure to detect a microbial contamination | 80 | 40 | 2.0 | |
| Sum | 3415 | 1397 | ||
| Mean | 7 | |||