| 1 | Drug-related morbidity (DRM) preceded by a recognisable drug therapy problem (DRP) |
| 2 | Given the DRP, the DRM would have been reasonably foreseeable |
| 3 | The cause of DRM would have been identifiable with reasonable probability (above criteria probable or definite for causality) |
| 4 | The cause of the DRM could have been reasonably controllable within the context and objectives of therapy |