Table 3 Predictive value of co-occurrence of a medical incident commonly captured by automated data systems and a suspect prescribing discrepancy

Incident/example of suspect discrepancy	Occurrences (n)*	Adverse drug events (n)	Positive predictive value (n/n) (95% CI)
Pain†/analgesic discrepancy	59	22	0.37 (0.25 to 0.51)
High blood pressure†/antihypertensive discrepancy	32	8	0.33 (0.16 to 0.55)
Renal insufficiency†/angiotensin blocker discrepancy	14	4	0.29 (0.10 to 0.58)
Low blood pressure†/antihypertensive discrepancy	34	6	0.18 (0.07 to 0.35)
Fever†/antibiotic discrepancy	28	2	0.07 (0.01 to 0.25)

*Episode types that had at least 10 occurrences are included.
†Pain, new or worse pain; Fever, temperature >38°C; High blood pressure, new systolic blood pressure >185, or diastolic blood pressure >105, or an increase in systolic or diastolic blood pressure of 30 mm; Low blood pressure, new systolic blood pressure <95, or a drop in systolic blood pressure of 30 mm; Renal insufficiency, new creatinine increase >0.5 mg/dl.