Table 4 Determinants of preventable adverse drug events
PredictorORunadjusted (95% CI)ORadjusted* (95% CI)
No. of dosing errors1.16 (1.09 to 1.23)1.05 (0.92 to 1.21)
No. of therapeutic errors2.22 (1.77 to 2.78)1.98 (1.53 to 2.56)
No. of transcription errors1.19 (1.12 to 1.26)1.12 (1.01 to 1.25)
Age
    Lowest to 340.27 (0.06 to 1.14)
    35 to 490.51 (0.21 to 1.23)
    50 to 640.55 (0.27 to 1.11)
    65 to 791.26 (0.75 to 2.10)
    80 to highest2.00 (1.22 to 3.25)1.63 (0.92 to 2.90)
Gender (male is reference)0.88 (0.54 to 1.42)
No. of medication errors1.07 (1.05 to 1.10)0.98 (0.90 to 1.05)
No. of medication orders1.07 (1.04 to 1.09)1.00 (0.96 to 1.05)
Therapeutic area (ATC code)
    A10 (antidiabetics)2.24 (1.23 to 4.08)1.50 (0.73 to 3.09)
    B01 (anticoagulants)1.35 (0.83 to 2.17)
    B03 (drugs for anaemia)2.39 (1.29 to 4.42)1.79 (0.86 to 3.71)
    H02 (corticosteroids1.34 (0.76 to 2.37)
    J01 (antibiotics for systemic use)2.99 (1.83 to 4.87)1.48 (0.82 to 2.68)
    M01 (anti-inflammatory drugs)1.00 (0.47 to 2.12)
    N02 (analgesics)2.07 (1.27 to 3.38)1.30 (0.72 to 2.32)
    N03 (antiepileptics)1.11 (0.37 to 3.31)
    N05 (psycholeptics)2.16 (1.33 to 3.50)1.44 (0.80 to 2.58)
    M04 (drugs for gout)2.21 (0.57 to 8.52)
  • Significant values are shown in bold. *Adjusted for the confounding factors, which contributed significantly to the model.