Table 2

Case-mix and treatment factors included in the multivariate logistic regression model for AL and mortality after colon and rectal carcinoma resections

		AL		Mortality
		OR	95% CI	OR	95% CI
Case-mix factors
Age		0.99	0.98 to 1.02	2.65	2.33 to 3.04
Gender	Male	1.31	1.11 to 1.55	1.82	1.39 to 2.37
ASA	2	1.01	0.84 to 1.22	3.09	1.54 to 6.17
	3+	1.00	0.80 to 1.24	6.44	3.46 to 13.12
BMI		0.91	0.74 to 1.13	0.99	0.97 to 1.02
Two or more comorbidities		0.88	0.70 to 1.10	1.17	0.82 to 1.67
Cardiovascular disease		0.85	0.70 to 1.04	1.21	0.90 to 1.62
Pulmonary disease		0.92	0.71 to 1.20	1.44	1.06 to 1.97
Diabetes		0.99	0.77 to 1.28	1.12	0.81 to 1.55
Crohn's disease		1.06	0.43 to 2.60	1.35	0.36 to 4.98
Preoperative blood loss		0.72	0.42 to 1.25	0.68	0.23 to 2.00
Steroid treatment		1.27	0.81 to 2.00	1.25	0.72 to 2.15
Renal disease		1.34	1.01 to 1.78	0.91	0.62 to 1.34
Abdominal surgical history		1.03	0.87 to 1.22	0.87	0.67 to 1.14
T stage	T3	1.03	0.87 to 1.21	1.05	0.81 to 1.36
	T4	1.13	0.78 to 1.64	1.22	0.71 to 2.10
Additional resection		1.20	0.88 to 1.64	0.96	0.59 to 1.55
Urgent resection		1.32	1.01 to 1.73	2.18	1.60 to 2.98
Tumour location	Transverse colon	1.93	1.49 to 2.50	1.25	0.89 to 1.76
	Sigmoid	1.68	1.33 to 2.11	0.70	0.50 to 1.00
	Rectum	2.22	1.49 to 3.29	1.04	0.52 to 2.04
Treatment factors
Neoadjuvant therapy	5×5	1.70	1.13 to 2.54	0.88	0.42 to 1.85
	Chemoradiotherapy	1.33	0.84 to 2.09	0.30	0.09 to 0.98
Defunctioning stoma		0.54	0.42 to 0.70	1.15	0.69 to 1.89
Transfusion		4.27	3.56 to 5.12	4.06	3.14 to 5.25

Age and BMI were analysed as continuous variables.
Bold numbers are significant ORs (p<0.05).
AL, anastomotic leakage; ASA, American Society of Anesthesiologists score; BMI, body mass index.