Table 1

Variation among numbers of ADRs listed in prescribing information of equivalent top-selling drugs marketed in the USA, Canada, the UK and Australia

	ADRs				Median
Drug name	US (N)	Canada (N)	UK (N)	Australia (N)	Median
Aripiprazole	221	216	110	352	219
Atorvastatin	55	84	77	53	66
Bevacizumab	127	793	137	101	132
Clopidogrel	57	133	76	109	93
Duloxetine	172	241	133	196	184
Enoxaparin	58	56	46	53	55
Erythropoetin alfa	61	131	53	54	58
Escitalopram	186	564	90	343	265
Esomeprazole	180	176	60	69	123
Etanercept	75	231	116	86	101
Fluticasone/salmeterol	116	121	47	40	82
Infliximab	132	319	204	174	189
Montelukast	92	77	52	66	72
Olanzapine	184	185	93	101	143
Oxycodone CR	100	132	106	112	109
Pegfilgrastim	22	71	50	58	54
Pioglitazone	38	49	40	56	45
Quetiapine	322	143	90	119	131
Rosuvastatin	42	86	41	36	42
Venlafaxine ER	452	507	112	136	294
Overall	108	138	84	94	105

ADR, adverse drug reaction; CR, controlled release; ER, extended release.