Summary of studies implementing combination interventions
| Study | Outcomes measured | Results |
|---|---|---|
| Clark (2011) | Appropriate prophylaxis prescription | After implementation, appropriate VTE prophylaxis prescription increased from 56% to 96%, but waned over time to 69% |
| Gallagher (2009) | Prophylaxis prescription | Prophylaxis prescription significantly increased (74% vs 48%, p=0.01) |
| VTE | VTE events significantly decreased (risk ratio 0.68, 95% CI 0.47 to 0.99, p=0.04) | |
| Stinnett (2005) | Prophylaxis prescription | Prophylaxis prescription increased after implementation (71% vs 43%) |
| Maynard (2010) | Prophylaxis prescription | VTE prophylaxis prescription significantly increased each year for 3 years from 58% at baseline to 78% to 93% (p<0.001) |
| VTE | Hospital acquired VTE decreased significantly (risk ratio 0.69, 95% CI 0.47 to 0.79) | |
| Preventable VTE | Preventable VTE decreased significantly by 86% (95% CI 0.06 to 0.31) |
VTE, venous thromboembolism.