Incidence of adverse drug events and medication errors
| Adverse drug events | N | Patient-days | ADEs | Incidence* | 95% CI | Rate† | 95% CI |
|---|---|---|---|---|---|---|---|
| Total | 1189 | 12 691 | 480 | 37.8 | 34.4 to 41.2 | 40.4 | 36.8 to 44.0 |
| Age category | |||||||
| Neonates (<1 month) | 252 | 4757 | 53 | 11.1 | 8.1 to 14.1 | 21.0 | 15.4 to 26.7 |
| LBW neonates, NICU | 69 | 3270 | 44 | 13.5 | 9.5 to 17.4 | 63.8 | 44.9 to 82.6 |
| Non-LBW neonates, NICU | 100 | 944 | 2 | 2.1 | 0.26 to 7.7 | 2.0 | 0.24 to 7.2 |
| General paediatric ward | 83 | 543 | 7 | 12.9 | 5.2 to 26.6 | 8.4 | 3.4 to 17.4 |
| Infants (1 month=< <1 year) | 174 | 1923 | 84 | 43.7 | 34.3 to 53.0 | 48.3 | 38.0 to 58.6 |
| Preschoolers (1 year =< <7 year s) | 465 | 3425 | 157 | 45.8 | 38.7 to 53.0 | 33.8 | 28.5 to 39.0 |
| School-age children (7 years=< <13 years) | 189 | 1459 | 73 | 50.0 | 38.6 to 61.5 | 38.6 | 29.8 to 47.5 |
| Teenagers (13 years=< <19 years) | 98 | 1081 | 112 | 103.6 | 84.4 to 122.8 | 114.3 | 93.1 to 135.5 |
| Adults (19 years=<) | 11 | 46 | 1 | 21.7 | 0.55 to 121.1 | 9.1 | 0.23 to 50.7 |
| Ward category | |||||||
| Paediatric ward | 704 | 7007 | 364 | 51.9 | 46.6 to 57.3 | 51.7 | 46.4 to 57.0 |
| NICU | 169 | 4214 | 46 | 10.9 | 7.8 to 14.1 | 27.2 | 19.4 to 35.1 |
| LBW neonates | 69 | 3270 | 44 | 13.5 | 9.5 to 17.4 | 63.8 | 44.9 to 82.6 |
| Non-LBW neonates | 100 | 944 | 2 | 2.1 | 0.26 to 7.7 | 2.0 | 0.24 to 7.2 |
| PICU | 18 | 157 | 2 | 12.7 | 1.5 to 46.0 | 11.1 | 1.3 to 40.1 |
| ICU | 37 | 107 | 9 | 84.1 | 38.5 to 159.7 | 24.3 | 11.1 to 46.2 |
| Emergent care unit | 98 | 197 | 11 | 55.8 | 22.8 to 88.8 | 11.2 | 4.6 to 17.9 |
| Adult ward | 163 | 1009 | 48 | 47.6 | 34.1 to 61.0 | 29.4 | 21.1 to 37.8 |
| Medication errors | N | Patient-days | Medication errors | Incidence* | 95% CI | Rate† | 95% CI |
| Total | 1189 | 12 691 | 826 | 65.1 | 60.6 to 69.5 | 69.5 | 64.7 to 74.2 |
| Age category | |||||||
| Neonates (<1 month) | 252 | 4757 | 161 | 33.8 | 28.6 to 39.1 | 63.9 | 54.0 to 73.8 |
| LBW neonates, NICU | 69 | 3270 | 112 | 34.3 | 27.9 to 40.6 | 162.3 | 132.3 to 192.4 |
| Non-LBW neonates, NICU | 100 | 944 | 36 | 38.1 | 25.7 to 50.6 | 36.0 | 24.2 to 47.8 |
| General paediatric ward | 83 | 543 | 13 | 23.9 | 10.9 to 37.0 | 15.7 | 7.1 to 24.2 |
| Infants (1 month=< <1 year) | 174 | 1923 | 70 | 36.4 | 27.9 to 44.9 | 40.2 | 30.8 to 49.7 |
| Preschoolers (1 year =< <7 year) | 465 | 3425 | 283 | 82.6 | 73.0 to 92.3 | 60.9 | 53.8 to 68.0 |
| School-age children (7 year=< <13 year) | 189 | 1459 | 175 | 119.9 | 102.2 to 137.7 | 92.6 | 78.9 to 106.3 |
| Teenagers (13 year=< < 19 year) | 98 | 1081 | 125 | 115.6 | 95.4 to 135.9 | 127.6 | 105.2 to 149.9 |
| Adults (19 year=<) | 11 | 46 | 12 | 260.9 | 113.3 to 408.5 | 109.1 | 47.4 to 170.8 |
| Ward category | |||||||
| Paediatric ward | 704 | 7007 | 440 | 62.8 | 56.9 to 68.7 | 62.5 | 56.7 to 68.3 |
| NICU | 169 | 4214 | 148 | 35.1 | 29.5 to 40.8 | 87.6 | 73.5 to 101.7 |
| LBW neonates | 69 | 3270 | 112 | 34.3 | 27.9 to 40.6 | 162.3 | 132.3 to 192.4 |
| Non-LBW neonates | 100 | 944 | 36 | 38.1 | 25.7 to 50.6 | 36.0 | 24.2 to 47.8 |
| PICU | 18 | 157 | 1 | 6.4 | 0.16 to 35.5 | 5.6 | 0.14 to 31.0 |
| ICU | 37 | 107 | 15 | 140.2 | 69.2 to 211.1 | 40.5 | 20.0 to 61.1 |
| Emergent care unit | 98 | 197 | 82 | 416.2 | 326.1 to 506.3 | 83.7 | 65.6 to 101.8 |
| Adult ward | 163 | 1009 | 140 | 138.8 | 115.8 to 161.7 | 85.9 | 71.7 to 100.1 |
ADEs, adverse drug events; ICU, intensive care unit; LBW, low birth weight; NICU, neonatal intensive care unit; PICU, paediatric intensive care unit.
*Per 1000 patient-days.
†Per 100 admissions.