Table 2

Top drug classes that were overridden in the outpatient setting

Total no. of ordersAlerts triggeredPercentage of orders that triggered an alertAlerts overridden (n=107 812)
Drug classnn% (no. of alerts/total no. of alerts)% (no. of alerts/total no. of orders)n%
Non-antibiotic sulfonamides (coxibs)16871800.710.715787.2
Opioids106 972545120.65.1460584.5
Non-antibiotic sulfonamides (without coxibs)78 9476362.40.852181.9
Aspirin and non-steroidal anti-inflammatory drugs* (without coxibs)89 59024439.32.7182774.8
ACE inhibitors and angiotensin receptor blockers76 6395972.30.843873.4
Cephalosporins and other beta-lactams15 93314005.38.8100972.1
Penicillins50 35113655.22.761144.8
Sulfonamide antibiotics24 4123471.31.48524.5
Other drugs1 550 65913 988530.911 09279.3
Monoclonal antibodies340100.300
Contrast media100000
Total1 995 53126 408100.1 (rounded to 100)1.320 34577.0