Outcome of each respective trigger in relation to adverse events (AEs) and no-harm incidents, sorted by positive predictive value (PPV) in total, % for the respective module
| Triggers n=38 | n (%) of records with ≥1 of each respective trigger | n of triggers detected in primary review | n of triggers related to AEs | PPV, % | n of triggers related to no-harm incidents | PPV, % | n of triggers related to AEs and no-harm incidents | PPV in total, % | Clinical relevance, index value | Comp-rehen-sibility, index value | Utility, index value |
| Care module | 2 180 | 621 | 28.5 | 375 | 17.2 | 996 | 45.7 | ||||
| Fall | 117 (19.5) | 204 | 66 | 32.4 | 130 | 63.7 | 196 | 96.1 | 1.00 | 0.89 | 0.67 |
| Documentation of mistake or dissatisfaction with care | 42 (7.0) | 66 | 10 | 15.2 | 44 | 66.7 | 54 | 81.8 | 1.00 | 1.00 | 1.00 |
| Deviation from normal course after invasive procedure/surgical treatment | 13 (2.2) | 29 | 21 | 72.4 | 2 | 6.9 | 23 | 79.3 | 0.67 | 0.78 | 0.56 |
| Treatment* | 36 (6.0) | 46 | 21 | 45.7 | 12 | 26.1 | 33 | 71.7 | 0.67 | 0.67 | 0.67 |
| Healthcare-associated infection | 84 (14.0) | 108 | 76 | 70.4 | 0 | 0.0 | 76 | 70.4 | 1.00 | 1.00 | 0.89 |
| Pressure ulcer | 66 (11.0) | 103 | 65 | 63.1 | 0 | 0.0 | 65 | 63.1 | 1.00 | 1.00 | 1.00 |
| Moderate/severe agitation and/or acute confusion/delirium† | 28 (4.7) | 35 | 13 | 37.1 | 8 | 22.9 | 21 | 60.0 | 0.67 | 0.67 | 0.67 |
| Escape from home/special accommodation* | 5 (0.8) | 5 | 0 | 0.0 | 3 | 60.0 | 3 | 60.0 | 0.78 | 1.00 | 0.78 |
| Distended urinary bladder | 20 (3.3) | 28 | 6 | 21.4 | 9 | 32.1 | 15 | 53.6 | 1.00 | 1.00 | 1.00 |
| Insufficient oral health | 40 (6.7) | 45 | 17 | 37.8 | 0 | 0.0 | 17 | 37.8 | 1.00 | 1.00 | 1.00 |
| Moderate/severe worry, anxiety, suffering, existential pain and/or psychological pain | 75 (12.5) | 268 | 40 | 14.9 | 58 | 21.6 | 98 | 36.6 | 1.00 | 0.89 | 1.00 |
| Cardiac arrest and/or deterioration in vital signs† | 53 (8.8) | 104 | 36 | 34.6 | 2 | 1.9 | 38 | 36.5 | 0.89 | 1.00 | 0.89 |
| Blood vessel, skin and/or tissue harm | 137 (22.8) | 253 | 91 | 36.0 | 0 | 0.0 | 91 | 36.0 | 0.89 | 0.78 | 0.89 |
| Moderate/severe pain | 155 (25.8) | 440 | 78 | 17.7 | 60 | 13.6 | 138 | 31.4 | 1.00 | 1.00 | 1.00 |
| Moderate/severe gastrointestinal problem† | 108 (18.0) | 188 | 33 | 17.6 | 25 | 13.3 | 58 | 30.9 | 1.00 | 1.00 | 1.00 |
| Other | 44 (7.3) | 122 | 21 | 17.2 | 16 | 13.1 | 37 | 30.3 | 0.50 | 0.75 | 0.50 |
| Neurological impairment and/or harm | 29 (4.8) | 33 | 9 | 27.3 | 0 | 0.0 | 9 | 27.3 | 0.78 | 0.78 | 0.78 |
| Advanced medical device† | 25 (4.2) | 34 | 3 | 8.8 | 6 | 17.6 | 9 | 26.5 | 0.89 | 0.89 | 0.78 |
| Undernutrition | 43 (7.2) | 52 | 13 | 25.0 | 0 | 0.0 | 13 | 25.0 | 0.89 | 1.00 | 0.78 |
| Threats, violence and/or improper contact* | 2 (0.3) | 5 | 1 | 20.0 | 0 | 0.0 | 1 | 20.0 | 0.67 | 0.89 | 0.78 |
| Self-inflicted harm* | 5 (0.8) | 6 | 1 | 16.7 | 0 | 0.0 | 1 | 16.7 | 0.78 | 1.00 | 0.67 |
| Deep vein thrombosis and/or pulmonary embolism* | 5 (0.8) | 6 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 | 1.00 | 1.00 | 0.89 |
| Laboratory module | 80 | 13 | 16.3 | 7 | 8.8 | 20 | 25.0 | ||||
| Abnormal sodium value* | 8 (1.3) | 12 | 8 | 66.7 | 1 | 8.3 | 9 | 75.0 | 0.50 | 0.83 | 0.33 |
| Abnormal glucose value* | 21 (3.5) | 30 | 4 | 13.3 | 4 | 13.3 | 8 | 26.7 | 1.00 | 1.00 | 0.86 |
| Abnormal potassium value* | 10 (1.7) | 13 | 1 | 7.7 | 2 | 15.4 | 3 | 23.1 | 0.50 | 0.83 | 0.33 |
| Increased creatinine value* | 12 (2.0) | 20 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 | 0.50 | 0.83 | 0.33 |
| Abnormal calcium value* | 5 (0.8) | 5 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 | 0.50 | 0.50 | 0.33 |
| Medication module | 673 | 95 | 14.1 | 113 | 16.8 | 208 | 30.9 | ||||
| Adverse drug event/adverse drug reaction | 62 (10.3) | 80 | 52 | 65.0 | 16 | 20.0 | 68 | 85.0 | 1.00 | 1.00 | 0.89 |
| Drug management | 92 (15.3) | 137 | 10 | 7.3 | 70 | 51.1 | 80 | 58.4 | 0.83 | 0.67 | 0.80 |
| Drug that requires follow-up with blood sampling | 141 (23.5) | 166 | 17 | 10.2 | 19 | 11.4 | 36 | 21.7 | 0.78 | 1.00 | 0.78 |
| Absence of in-depth drug review* | 78 (13.0) | 80 | 8 | 10.0 | 2 | 2.5 | 10 | 12.5 | 0.88 | 1.00 | 0.88 |
| Treatment with drugs that increase the risk for haemorrhage* | 98 (16.3) | 110 | 6 | 5.5 | 6 | 5.5 | 12 | 10.9 | 0.89 | 1.00 | 0.78 |
| Treatment with at least 10 drugs* | 98 (16.3) | 100 | 2 | 2.0 | 0 | 0.0 | 2 | 2.0 | 0.63 | 0.75 | 0.50 |
| Continuity and transition module | 1 098 | 295 | 26.9 | 161 | 14.7 | 456 | 41.5 | ||||
| Documentation related to insufficient coordination of care, communication and/or information‡ | 56 (9.3) | 72 | 24 | 33.3 | 40 | 55.6 | 64 | 88.9 | 0.89 | 1.00 | 0.89 |
| Absence of and/or deviation from care plan‡ | 70 (11.7) | 98 | 25 | 25.5 | 17 | 17.3 | 42 | 42.9 | 1.00 | 1.00 | 0.75 |
| Unplanned contact with physician and/or registered nurse | 228 (38.0) | 658 | 178 | 27.1 | 85 | 12.9 | 262 | 40.0 | 0.78 | 0.89 | 0.78 |
| Unplanned change in care-providing unit | 157 (26.2) | 213 | 62 | 29.1 | 16 | 7.5 | 78 | 36.6 | 0.89 | 1.00 | 0.89 |
| Absence of a coordinated individual care plan when care is provided by several caregivers‡ | 56 (9.3) | 57 | 6 | 10.5 | 3 | 5.3 | 9 | 15.8 | 1.00 | 0.89 | 0.78 |
| Total | 518 (86.3) | 4 031 | 1 024 | 25.4 | 647 | 16.3 | 1 671 | 41.7 |
*The trigger was removed in the fourth Delphi round.
† The trigger was slightly renamed in the fourth Delphi round.
‡The trigger was merged with another trigger in the fourth Delphi round.