Poor population† | Low/middle-income pensioners | Low-income non-pensioners | Middle-income non-pensioners | High-income population† | ||||||
OR | 95% CI | OR | 95% CI | OR | 95% CI | OR | 95% CI | OR | 95% CI | |
Baseline level of IMNA (intercept, ) | 0.311 | 0.297 to 0.325 | 0.241 | 0.235 to 0.246 | 0.243 | 0.240 to 0.247 | 0.243 | 0.238 to 0.249 | 0.251 | 0.207 to 0.303 |
Baseline trend per week of IMNA (preintervention slope, )‡ | 1.001 | 0.999 to 1.002 | 0.997 | 0.997 to 0.998 | 1.000 | 0.999 to 1.001 | 1.000 | 0.999 to 1.001 | 1.003 | 0.996 to 1.010 |
News release | ||||||||||
Immediate effect of the event (level change in IMNA rate from previous week, )§ | 0.862 | 0.819 to 0.907 | 0.992 | 0.966 to 1.019 | 0.963 | 0.947 to 0.980 | 0.986 | 0.957 to 1.015 | 1.102 | 0.850 to 1.428 |
Long-term effect of the event (gradual change in slope, per week, )¶ | 0.999 | 0.997 to 1.001 | 0.992 | 0.991 to 0.993 | 0.998 | 0.997 to 0.998 | 0.997 | 0.996 to 0.998 | 0.984 | 0.975 to 0.993 |
Introduction of the fixed copayment** | ||||||||||
Immediate effect of the event (level change in IMNA rate from previous week, )§ | 1.315 | 1.216 to 1.422 | 1.370 | 1.319 to 1.423 | 1.047 | 1.015 to 1.079 | 1.038 | 0.985 to 1.093 | 1.231 | 0.804 to 1.882 |
Long-term effect of the event (gradual change in slope, per week, )¶ | 0.962 | 0.948 to 0.976 | 1.058 | 1.052 to 1.064 | 1.023 | 1.015 to 1.030 | 1.028 | 1.015 to 1.041 | 1.104 | 1.020 to 1.194 |
Change in coinsurance scheme** | ||||||||||
Immediate effect of the event (level change in IMNA rate from previous week, )§ | 0.957 | 0.882 to 1.039 | 0.949 | 0.907 to 0.993 | 0.941 | 0.901 to 0.983 | 0.994 | 0.922 to 1.073 | 0.659 | 0.415 to 1.048 |
Long-term effect of the event (gradual change in slope, per week, )¶ | 1.029 | 1.025 to 1.032 | 0.982 | 0.980 to 0.985 | 0.999 | 0.997 to 0.999 | 0.996 | 0.994 to 0.998 | 0.988 | 0.969 to 1.008 |
Suspension of fixed copayment | ||||||||||
Immediate effect of the event (level change in IMNA rate from previous week, )§ | 0.676 | 0.642 to 0.711 | 0.883 | 0.865 to 0.912 | 0.927 | 0.912 to 0.942 | 0.856 | 0.833 to 0.880 | 0.922 | 0.720 to 1.180 |
Long-term effect of the event (gradual change in slope, per week, )¶ | 0.995 | 0.994 to 0.995 | 0.999 | 0.998 to 0.999 | 0.999 | 0.999 to 0.999 | 1.000 | 1.000 to 1.001 | 1.002 | 1.000 to 1.005 |
*Models were adjusted for the characteristics of patients, FPs and PC centres as well as for seasonality (week of the month and month of the year).
†Includes pensioners and non-pensioners.
‡Bold numbers indicate statistically significant difference from zero.
§This row reports the level change in IMNA prevalence (OR)—that is, the increase/decrease in IMNA prevalence—immediately after the event week; bold numbers indicate statistically significant differences (95% confidence probability).
¶This row reports the period trend in OR per 1-week increase. Bold numbers indicate statistically significant differences between each period slope and initial period slope.
**The end of the third period and the beginning of the fourth period are not the same for all population profiles. For non-pensioner only profiles (40% and 50%) the period change was in the 83rd week, for pensioner only profiles (40%) the period change was in the 88th week, and for pensioner and non-pensioner profile groups the period change was in the 85th week.
FP, family physician; IMNA, initial medication non-adherence; PC, primary care.