Table 2

Multilevel negative binomial regression results

Adjusted results*
IRR (95% CI)P value
CLABSI rate
 Preintervention slope0.95 (0.77 to 1.19)0.67
 Shift in rates preintervention to intervention0.90 (0.72 to 1.11)0.32
 Intervention slope0.71 (0.53 to 0.96)0.03
 Intervention slope change0.75 (0.52 to 1.08)0.13
Central line utilisation rate
 Preintervention slope0.97 (0.94 to 0.99)0.004
 Shift in rates preintervention to intervention1.01 (0.99 to 1.03)0.51
 Intervention slope0.94 (0.91 to 0.96)<0.001
 Intervention slope change0.97 (0.93 to 1.00)0.09
CAUTI rate
 Preintervention slope0.96 (0.80 to 1.15)0.66
 Shift in rates preintervention to intervention0.94 (0.79 to 1.12)0.48
 Intervention slope0.76 (0.60 to 0.96)0.02
 Intervention slope change0.79 (0.59 to 1.06)0.12
Urinary catheter utilisation rate
 Preintervention slope0.95 (0.93 to 0.97)<0.001
 Shift in rates preintervention to intervention1.00 (0.99 to 1.02)0.73
 Intervention slope0.93 (0.91 to 0.95)<0.001
 Intervention slope change0.98 (0.95 to 1.01)0.14
  • *All models were adjusted for teaching status, urban or rural hospital location, type of hospital ownership, ICU bed size, ICU type, and whether or not the ICU focused its programme implementation efforts on the relevant infection (CLABSI, CAUTI or both).

  • CAUTI, catheter-associated urinary tract infection; CLABSI, central line-associated bloodstream infection; ICU, intensive care unit; IRR, incidence rate ratio.