Table 2

Comparison of diagnostic decision pathway with MDCalc and PE-Dx CDS

MDCalc (web-based CDS)PE-Dx CDS
Integration with EHR
Not integrated in EHR; separate websiteIntegrated in EHR
Wells’ score (seven criteria)
 InitiationUser needs to open browser, type MDCalc PE in search engine in browser and click on URL for MDCalc websiteUser clicks on PE-Dx button in ED Navigator
 Criteria responsesUser does not have to answer all (7) criteria before obtaining a scoreUser has to address all (7) criteria before obtaining the Wells’ score
 Auto-populationNo criteria are auto-populated; therefore, the user may need to navigate between the EHR and MDCalc to search for relevant informationOne criterion (heart rate >100) is auto-populated; user may need to navigate within the EHR to search for other relevant information
PERC rule (eight criteria)
 InitiationUser must access a different website within MDCalc to review PERC criteriaPERC is integrated in CDS and becomes active when indicated per hospital policy
 Criteria responsesUser must respond yes to only one criterion to receive PERC-positive resultUser must respond yes to only one criterion to receive PERC-positive result
 Auto-populationDoes not auto-populate, nor copy results from Wells’ criteria. Therefore, user may need to navigate between the EHR and MDCalc to search for relevant informationAuto-populates three questions (age, heart rate, O2 saturation) and copies forward responses from comparable Wells’ criteria (prior PE or deep vein thrombosis, hemoptysis). Therefore, user must address only three criteria (recent trauma or surgery, exogenous oestrogen, unilateral leg swelling)
Risk assessment and decision-making
 Result/scoreProvides the user with a score (eg, 3.0 points for Wells’ score) and compares that score with the population (eg, moderate-risk group: 16.2% chance of PE in ED population)Provides the user with a score
 Recommendations/next stepsProvides the user with suggestion for next steps; suggestion uses two different models, which can be confusingProvides the user with a single recommendation in accord with hospital policy and established guidelines49
 Order *Does not automatically provide option to enter an orderProvides the option to go to CPOE to order D-dimer or CTA scan when applicable
 Documentation *Allows user to copy results (summary and scores on individual questions) into an EHR note, but user must register to use the featureAllows the user to populate the results and recommendation directly into his/her note
  • *The automated creation of an order and documentation of the decision were not tested in this study, but are available in the implemented version of PE-Dx CDS.

  • CPOE, computerized provider order entry; CTA, CT angiography; ED, emergency department; PE, pulmonary embolism; PE-Dx CDS, clinical decision support for pulmonary embolism diagnosis; PERC, pulmonary embolism rule-out criteria.