Procedure prescription sizes in February 2017 and May 2019
| Procedure | Total N (%) | Mean (SD) prescription size in pills of 5 mg oxycodone | P value* | |||
| Preguideline release | Postguideline v1 release | Postguideline v2 release | Postguideline v3 release | |||
| Minor hernia repair | 10 455 (29.0) | 25 (17) | 19 (12) | 13 (8) | 11 (8) | <0.001 |
| Major hernia repair | 1921 (5.3) | 28 (18) | 22 (13) | 16 (10) | 14 (9) | <0.001 |
| Vaginal hysterectomy | 1755 (4.9) | 23 (13) | 23 (13) | 17 (12) | 14 (7) | <0.001 |
| Total abdominal hysterectomy | 1347 (3.7) | 29 (18) | 30 (52) | 18 (9) | 16 (7) | <0.001 |
| Open colectomy | 1427 (4.0) | 34 (33) | 28 (30) | 18 (16) | 15 (10) | <0.001 |
| Laparoscopic colectomy | 1426 (4.0) | 27 (19) | 22 (11) | 16 (11) | 15 (11) | <0.001 |
| Laparoscopic hysterectomy | 3773 (10.5) | 25 (14) | 22 (14) | 16 (10) | 14 (8) | <0.001 |
| Laparoscopic appendectomy | 3599 (10.0) | 22 (12) | 17 (15) | 11 (6) | 10 (5) | <0.001 |
| Laparoscopic cholecystectomy | 10 319 (28.6) | 23 (16) | 17 (10) | 12 (9) | 11 (7) | <0.001 |
| Total | 36 022 | 25 (17) | 20 (17) | 14 (9) | 12 (8) | <0.001 |
*P value is for the pair-wise comparison of before any guideline release to after the final guideline release.