Table 5

CMOCs for final programme theory

CMOCs—participation
ContextMechanismOutcomes when M presentOutcomes when M not present
1. Recruitment:
time point and location (community pharmacy (CP), hospital, clinic) of patient recruitment for participation.
Organisational support for recruitment.
M1: mandate, perception of benefit by recruiters.
M3: patients trust HCPs who recommends MR.
M10: pharmacists or designated recruiters take responsibility for identifying and consenting patients.
O1: patients provide informed consent to participate in MR.17–19 53 65 66 O2: patient recruitment/participation rates are low.37 42
2. Patients’ experience and attitudes to pharmacists’ clinical role.M3: trust in pharmacist skill.
M5: perception of benefit from pharmacist-led MR by patients.
O1: acceptance of referral to and participation in pharmacist-led MR.37 O2: low rates of referral to and participation in pharmacist-led MR.36 46 53
O3: patients seek out specialists, GP or community pharmacist to address concerns or concerns are not met.37
3. Awareness of MR programmes and referral pathways by healthcare professionals.M4: recognition of pharmacists’ clinical and professional role by HCPs.
M5: pharmacists, doctors, other HCPs perceive benefit of an MR.
O4: increased referral to and/or uptake of MR.49 51 57 65 66 O5: low referral and/or uptake of MR.37–39 53 71–73
4. Systems and organisational structures support MR and facilitate its role integration.M1: mandate to perform MR.
M4: recognition and acceptance of MR by pharmacists as professional role.
M5: pharmacists’ perceive benefit from MR for patients and their professional standing.
O6: pharmacists perform MR as part of their routine practice.18–21 45 48 53 57 O7: pharmacists do not perform MR as part of routine practice.40 42
5. Location of MR appointment.M2: less effort required.
M6: patient preferences.
O1: patients participate in MR.17 23 76 O2: patients decline to participate in MR.37 38 40 41 52 74 75
6. Life after hospital has to be reorganised, regained.M7: patients’ weigh priorities against perceptions of benefit.O1: patients participate (schedule and attend) in MR.37 O2: patients do not participate (schedule or attend) in MR they agreed to in hospital.18 19 37 50 51 53 78
CMOC related to participation and process
7. Communication, collaboration, coordination and networksM2: less effort required.
M8: invitation to collaborate by pharmacists to doctors, or doctors to pharmacists.
O1: patients are more likely to participate.17 48 53 65
O4: doctors refer to MR.53 56 65–67
O8: all or most issues, for example, medication-related problems or patient problems, are identified and strategies to resolve them suggested or actioned.17–19 45 48 60
O10: pharmacists performing MR are aware when people are discharged.18–20 46 48 57–59 79 80 89
O9: issues may be missed and strategies to resolve issues cannot be easily actioned.22 23 75 80
O11: pharmacists or patients do not schedule appointments after discharge.40 41 72
O12: pharmacists are not aware when people have left hospital.39 42 44
CMOCs process
8. Information available to pharmacist before and during the MRM8: invitation to collaborate by other HCPs.
M9: pharmacists enabled to employ clinical skills and judgement.
O8: all or most issues, for example, medication-related problems or patient problems, are identified and strategies to resolve them suggested or actioned.17–19 45 48 60 65 O9: issues may be missed and strategies to resolve issues cannot be easily actioned.22 23 57 75 77 80
9. Regulations and standards guiding MRM10: pharmacist takes responsibility for MR outcomes.O13: MR becomes more than an assessment-focused service.
17–19 46 48
O14: MR constitutes an administrative rather than clinical assessment of medicines, limiting positive process and patient outcomes.22 23 57–59 75 80
  • CMOC, CMO configuration; GP, general practitioner; HCP, healthcare professional; MR, medication reviews.