Summary of logistic regression relating patient characteristics to the occurrence of an MDO
| Patients with a confirmed MDO (n=89) | Patients with no confirmed MDO (n=1961)* | Univariate analysis | Multivariate analysis | ||||
| OR (95% CI) | P value | OR (95% CI) | P value | Sensitivity p value† | |||
| Age, mean (SD) | 52.0 (17.4) | 49.4 (18.3) | 1.08‡ (0.98 to 1.19) | 0.112 | 1.11‡ (0.99 to 1.26) | 0.077 | 0.022 |
| Male, n (%) | 39 (44) | 801 (41) | 1.13 (0.85 to 1.51) | 0.407 | 1.12 (0.83 to 1.50) | 0.458 | 0.479 |
| Repeat medications, mean (SD) | 2.7 (3.5) | 2.8 (3.6) | 0.97 (0.94 to 1.04) | 0.601 | 0.94 (0.88 to 1.00) | 0.056 | 0.131 |
| Long-term conditions, mean (SD) | 2.9 (2.5) | 2.8 (2.3) | 1.03 (0.93 to 1.14) | 0.564 | 1.04 (0.92 to 1.17) | 0.548 | – |
| Consultation location, n (%)§ | |||||||
| Practice | 88 (99) | 1936 (99) | NA | NA | NA | NA | NA |
| Home | 1 (1) | 18 (1) | |||||
*Seven patients excluded due to missing covariate data.
†Excluding number of long-term conditions due to high multicollinearity (r=0.63 with number of medications; r=0.55 with age).
‡OR for a 10-year change in age.
§Not included in logistic model because only one patient with an MDO was seen at home.
MDO, missed diagnostic opportunity; NA, not applicable.