Table 2

Adjusted ORs (AORs) of in-hospital mortality among patients with COVID-19 admitted between March 2020 and February 2021

CharacteristicAll hospitalised patients (N=38 104)Patients with an ICU stay (N=16 756)
AOR95% CIP valueAOR95% CIP value
Month admitted
 Mar–AprReferenceReferenceReferenceReferenceReferenceReference
 May–Jun0.660.55 to 0.79<0.0010.710.58 to 0.880.002
 Jul–Aug0.670.57 to 0.78<0.0010.780.65 to 0.940.009
 Sep–Oct0.710.61 to 0.84<0.0010.810.67 to 0.990.037
 Nov–Dec0.720.63 to 0.82<0.0010.860.73 to 1.010.067
 Jan–Feb0.580.51 to 0.68<0.0010.710.60 to 0.85<0.001
Race
 WhiteReferenceReferenceReferenceReferenceReferenceReference
 Black or African American0.950.86 to 1.040.31.070.96 to 1.190.2
 Other1.331.16 to 1.52<0.0011.361.16 to 1.60<0.001
Age (standardised)1.881.78 to 1.99<0.0011.81.69 to 1.91<0.001
Sex
 FemaleReferenceReferenceReferenceReferenceReferenceReference
 Male1.271.19 to 1.36<0.0011.271.17 to 1.38<0.001
Insurance
 CommercialReferenceReferenceReferenceReferenceReferenceReference
 Medicaid1.130.96 to 1.320.21.140.95 to 1.370.14
 Medicare1.171.05 to 1.290.0031.241.10 to 1.39<0.001
 Other1.060.82 to 1.350.71.080.82 to 1.430.6
Comorbidity
 Obesity1.921.78 to 2.08<0.0011.761.60 to 1.93<0.001
 Asthma0.750.65 to 0.87<0.0010.630.54 to 0.74<0.001
 Chronic obstructive pulmonary disease0.870.80 to 0.950.0020.670.61 to 0.74<0.001
 Diabetes1.471.37 to 1.58<0.0011.371.26 to 1.49<0.001
 Hypertension0.930.85 to 1.020.10.960.87 to 1.070.5
 Heart failure0.580.52 to 0.64<0.0010.580.52 to 0.65<0.001
 Chronic ischaemic heart disease1.131.04 to 1.220.0031.090.99 to 1.200.077
 Chronic kidney disease0.870.79 to 0.950.0020.970.87 to 1.080.5
 Liver disease1.731.54 to 1.95<0.0011.741.51 to 2.00<0.001
 Neoplasms0.690.60 to 0.78<0.0010.780.66 to 0.910.002
 Transplant1.310.90 to 1.900.21.410.91 to 2.180.12
Elixhauser comorbidity index (standardised)2.42.30 to 2.50<0.0012.061.95 to 2.17<0.001
Social vulnerability index
 LowReferenceReferenceReferenceReferenceReferenceReference
 Mid-low0.970.85 to 1.110.70.930.79 to 1.090.4
 Mid-high0.920.80 to 1.050.20.870.74 to 1.020.087
 High1.10.96 to 1.270.21.030.87 to 1.210.8
Vital signs
 Respiratory rate ≥24 breaths/min2.172.02 to 2.34<0.0011.591.46 to 1.73<0.001
 Oxygen saturation <94%1.81.68 to 1.93<0.0011.551.43 to 1.68<0.001
 Temperature ≥38°C1.070.97 to 1.180.21.110.99 to 1.240.068
COVID-19 hospital prevalence
 Low (<10%)ReferenceReferenceReferenceReferenceReferenceReference
 Mid (10%–25%)1.251.13 to 1.38<0.0011.321.18 to 1.49<0.001
 High (>25%)1.411.23 to 1.61<0.0011.531.30 to 1.80<0.001
Hospital census comparison with 2019
 Equal (>−10% to <10%)ReferenceReferenceReferenceReferenceReferenceReference
 Less (<−10%)0.980.86 to 1.120.80.970.83 to 1.140.7
 More (>10%)1.010.91 to 1.120.91.10.97 to 1.250.12
  • ICU, intensive care unit.