Baseline characteristics for admissions with AMI, by study period
| Before lockdown | Since lockdown | All | Missing data % (n) | |
| Patients, n | 225 994 | 10 749 | 236 743 | |
| Hospitals, n | 186 | 186 | 186 | |
| Demographics | ||||
| Female, % (n) | 32.2 (72 667) | 30.3 (3 251) | 32.2 (75 918) | 0.3 (621) |
| Age (years), median (IQR) | 69.0 (58–79) | 68.0 (58–77) | 69.0 (58–79) | 0 (0) |
| Baseline characteristics | ||||
| Heart rate at hospitalisation (bpm), median (IQR) | 77 (66–90) | 77 (66–90) | 77 (66–90) | 3.4 (7960) |
| Systolic blood pressure (mm Hg), median (IQR) | 137 (120–156) | 140 (121–160) | 137 (120–157) | 3.3 (7826) |
| Initial creatinine, μmol/L, median (IQR) | 85 (71–105) | 83 (70–101) | 85 (71–104) | 4.6 (10 824) |
| Diagnosis | ||||
| STEMI | 35.7 (80 564) | 37.9 (4070) | 35.8 (84 634) | 0 (0) |
| NSTEMI | 64.4 (145 430) | 62.1 (6679) | 64.3 (152 109) | 0 (0) |
| GRACE | ||||
| Score, median (IQR) | 121 (96–151) | 117 (95–143) | 121 (96–151) | 18.4 (43 566) |
| Low, % (n) | 19.1 (35 628) | 21.4 (1863) | 19.4 (37 491) | |
| Intermediate, % (n) | 32.1 (59 278) | 35.0 (3049) | 32.3 (62 327) | |
| High, % (n) | 48.6 (89 563) | 43.6 (3796) | 48.3 (93 359) | |
| Killip class | ||||
| I, % (n) | 82.3 (166 682) | 85.5 (8263) | 82.4 (174 945) | 10.4 (24 511) |
| II, % (n) | 11.4 (23 106) | 9.3 (895) | 11.3 (24 001) | |
| III, % (n) | 4.6 (9320) | 3.6 (348) | 4.6 (9668) | |
| IV, % (n) | 1.7 (3459) | 1.7 (159) | 1.7 (3618) | |
| Comorbidities | ||||
| Diabetes, % (n) | 26.0 (58 767) | 25.0 (2685) | 26.0 (61 452) | 0 (0) |
| COPD, % (n) | 14.8 (33 539) | 15.6 (1568) | 14.8 (35 107) | 0 (0) |
| Chronic heart failure, % (n) | 6.4 (14 453) | 5.8 (623) | 6.4 (15 076) | 0 (0) |
| Chronic renal failure, % (n) | 6.9 (15 646) | 6.4 (684) | 6.9 (16 330) | 0 (0) |
| Cerebrovascular disease, % (n) | 7.3 (16 436) | 6.5 (696) | 7.2 (17 132) | 0 (0) |
| Peripheral vascular disease, % (n) | 4.0 (9109) | 3.8 (409) | 4.0 (9518) | 0 (0) |
| Hypertension, % (n) | 47.6 (107 532) | 46.7 (5016) | 47.5 (112 548) | 0 (0) |
| Previous MI, % (n) | 23.7 (47 647) | 22.9 (2145) | 23.7 (49 792) | 11.3 (26 692) |
| Previous angina, % (n) | 20.7 (40 919) | 18.3 (1683) | 20.6 (42 602) | 12.7 (30 083) |
| Previous PCI, % (n) | 15.4 (30 483) | 16.3 (1499) | 15.5 (31 982) | 12.6 (29 742) |
| Previous CABG, % (n) | 7.2 (14 324) | 6.6 (610) | 7.2 (14 934) | 12.5 (29 565) |
| In-hospital procedures | ||||
| Invasive coronary angiography, % (n) | 71.3 (160 795) | 73.1 (7841) | 71.3 (168 636) | 0.15 (354) |
| PCI, % (n) | 51.4 (116 202) | 56.7 (6094) | 51.7 (122 296) | 0 (0) |
| CABG, % (n) | 2.0 (4610) | 0.9 (96) | 2.0 (4706) | 0 (0) |
| Medications at discharge | ||||
| Aspirin, % (n) | 97.9 (167 286) | 98.0 (7994) | 97.9 (175 280) | 24.4 (57 682) |
| P2Y12 inhibitor, % (n) | 96.6 (165 723) | 97.7 (8062) | 96.6 (173 785) | 24.0 (56 849) |
| Beta blocker, % (n) | 96.1 (156 943) | 96.5 (7557) | 96.1 (164 500) | 27.7 (65 590) |
| ACEi or ARB, % (n) | 94.2 (148 284) | 94.5 (7275) | 94.2 (155 559) | 30.3 (71 643) |
| Statins, % (n) | 97.3 (168 402) | 97.6 (8118) | 97.3 (176 520) | 23.5 (55 639) |
| Lifestyle advice | ||||
| Cardiac rehabilitation, % (n) | 88.8 (159 999) | 88.4 (7652) | 88.8 (167 651) | 20.2 (47 903) |
| Smoking cessation advice, % (n) | 74.6 (48 821) | 78.1 (2320) | 74.6 (51 141) | 71.1 (168 331) |
| Dietary advice, % (n) | 89.8 (148 959) | 91.1 (7067) | 89.8 (156 026) | 26.6 (63 013) |
ACEi, angiotensin converting enzyme inhibitor; ARB, angiotensin receptor blocker; bpm, beats per minute; CABG, coronary artery bypass graft; COPD, chronic obstructive pulmonary disease; GRACE, Global Registry of Acute Coronary Events; MI, myocardial infarction; NSTEMI, non-ST segment elevation myocardial infarction; PCI, percutaneous coronary intervention; STEMI, ST-segment elevation myocardial infarction.