Single vs multi-lumen device use | ||||
Single lumen PICC, n (%) | Multi-lumen PICC, n (%) | OR (95% CI) | P value | |
All complications (DVT+CLABSI+occlusion) | 329 (6.6) | 819 (10.6) | 2.54 (1.61 to 4.02) | 0.001 |
DVT+CLABSI (no occlusion) | 199 (4) | 602 (7.8) | 2.13 (1.67 to 2.72) | <0.001 |
Reversible/irreversible occlusion | 135 (2.7) | 258 (3.3) | 3.40 (1.67 to 6.94) | 0.003 |
DVT/PE (thrombosis) | 36 (0.7) | 95 (1.2) | 2.04 (1.32 to 3.14) | 0.004 |
Confirmed/suspected CLABSI | 165 (3.3) | 511 (6.6) | 2.08 (1.62 to 2.67) | <0.001 |
Short-term vs long-term use | ||||
PICC in place ≥5 days, n (%) | PICC in place <5 days, n (%) | OR (95% CI) | P value | |
All complications (DVT+CLABSI+occlusion) | 1086 (10.3) | 62 (2.9) | 0.28 (0.21 to 0.38) | <0.001 |
DVT+CLABSI (no occlusion) | 757 (7.2) | 44 (2) | 0.29 (0.22 to 0.38) | <0.001 |
Reversible/irreversible occlusion | 373 (3.5) | 20 (0.9) | 0.30 (0.13 to 0.68) | 0.007 |
DVT/PE (thrombosis) | 116 (1.1) | 15 (0.7) | 0.67 (0.41 to 1.10) | 0.102 |
Confirmed/suspected CLABSI | 647 (6.1) | 29 (1.3) | 0.22 (0.16 to 0.31) | <0.001 |
Presence or absence of chronic kidney disease (CKD) | ||||
No CKD (%) | CKD (%) | OR (95% CI) | P value | |
All complications (DVT+CLABSI+occlusion) | 1000 (8.8) | 148 (10.6) | 1.12 (0.89 to 1.42) | 0.304 |
DVT+CLABSI (no occlusion) | 687 (6.1) | 114 (8.2) | 1.18 (0.94 to 1.48) | 0.139 |
Reversible/irreversible occlusion | 354 (3.1) | 39 (2.8) | 0.99 (0.67 to 1.46) | 0.938 |
DVT/PE (thrombosis) | 118 (1) | 13 (0.9) | 0.85 (0.37 to 1.97) | 0.686 |
Confirmed/suspected CLABSI | 573 (5.1) | 103 (7.4) | 1.27 (0.97 to 1.65) | 0.075 |
Results were estimated using mixed-effects logistic regression with hospital random intercepts to account for hospital-level correlation. Patient and device-level adjustments include age, gender, active cancer, history of DVT/PE, ICU placement, other catheters placed at time of insertion, vessel ratio, insertion zone and tip position. Created by the authors.
CLABSI, central line-associated bloodstream infection; DVT, deep vein thrombosis; ICU, intensive care unit; MAGIC, Michigan Appropriateness Guide for Intravenous Catheters; PE, pulmonary embolism; PICC, peripherally inserted central catheter.