Study outcomes | Control period (n=1060) | ERAS period (n=1337) | Effect measure | ||||
Primary endpoint | n | Mean (median; SD) | n | Mean (median; SD) | Mean difference | 95% CI | P value |
LOS | 979 | 8.55 (7; 3.87) | 1264 | 7.5 (7; 3.49) | −0.58 | −1.07, −0.09 | 0.021 |
Secondary endpoints | n/total | % | n/total | % | OR | 95% CI | P value |
LOS outliers | 81/1060 | 7.64 | 73/1337 | 5.46 | 1.02 | 0.58, 1.80 | 0.944 |
Complications | |||||||
Total | 285/1058 | 26.9 | 364/1336 | 27.2 | 1.22 | 0.88, 1.68 | 0.218 |
Medical | 148/1058 | 14.0 | 182/1336 | 13.6 | 1.20 | 0.79, 1.84 | 0.380 |
Only minor medical | 125/1058 | 11.8 | 133/1336 | 10.0 | 0.94 | 0.59, 1.49 | 0.770 |
Major medical | 22/1058 | 2.1 | 44/1336 | 3.3 | 2.13 | 0.98, 4.62 | 0.055 |
Surgical | 194/1058 | 18.3 | 257/1336 | 19.2 | 1.32 | 0.94, 1.85 | 0.109 |
Only minor surgical | 112/1058 | 10.6 | 151/1336 | 11.3 | 1.43 | 0.94, 2.19 | 0.093 |
Major surgical | 84/1058 | 7.9 | 108/1336 | 8.1 | 1.12 | 0.68, 1.85 | 0.636 |
Transfusions | 107/1058 | 10.1 | 120/1336 | 9.0 | 0.71 | 0.45, 1.12 | 0.136 |
ICU access | 144/1058 | 13.6 | 191/1336 | 14.3 | 0.97 | 0.61, 1.54 | 0.906 |
Inpatient mortality | 16/1060 | 1.51 | 21/1337 | 1.57 | 1.63 | 0.61, 4.38 | 0.316 |
30-day ED admissions | 61/1044 | 5.84 | 76/1316 | 5.78 | 1.51 | 0.88, 2.60 | 0.131 |
30-day hospital readmissions | 98/1044 | 9.39 | 105/1316 | 7.98 | 1.16 | 0.74, 1.81 | 0.511 |
30-day reinterventions | 78/1044 | 7.47 | 95/1316 | 7.22 | 1.47 | 0.89, 2.44 | 0.131 |
n | Mean (median; SD) | n | Mean (median; SD) | Mean difference | 95% CI | P value | |
Mean QoR score | 760 | 7.12 (7.2; 1.52) | 1002 | 7.46 (7.6; 1.37) | 0.24 | 0.01, 0.47 | 0.039 |
Mean QoR score - physical scale | 760 | 7.14 (7.3; 1.64) | 1002 | 7.56 (7.80; 1.50) | 0.33 | 0.08, 0.57 | 0.011 |
Mean QoR score - mental scale | 760 | 7.08 (7.60; 2.00) | 1002 | 7.26 (7.80; 1.97) | 0.08 | −0.24, 0.40 | 0.622 |
Well-being Visual Analogue Scale score | 813 | 6.72 (7; 1.72) | 1037 | 7.14 (7; 1.6) | 0.31 | 0.05, 0.57 | 0.021 |
ED, emergency department; ERAS, enhanced recovery after surgery; ICU, intensive care unit; LOS, length of stay; QoR, Quality of Recovery.