Overall assessments of the certainty of evidence
| Conclusion from MHS IV | Strength of evidence |
| Universal gloving has a small effect in reducing MDRO infections (mostly in the ICU setting) | Low |
| Contact precautions have mixed evidence for effect in reducing MDRO infections | Low |
| Cohorting may be part of an effective strategy to reduce MDRO infections in the setting of an outbreak | Low |
| Environmental decontamination may reduce MDRO infections | Low |
| Patient decolonisation can reduce MDRO infections in certain populations | Moderate |
| Bundled infection prevention and control practices in long-term care facilities have at most a small effect on rates of MDRO infections in the endemic setting | Low |
| Infective isolation makes little difference to psychological outcomes, but where it does make a difference this is primarily negative | Low |
| Non-infectious adverse events may be higher in patients in infective isolation compared with patients who are not isolated | Very Low |
ICU, Intensive care unit; MDROs, multidrug-resistant organisms; MHS, Making Healthcare Safer.