Any investigation | Blood tests | Imaging | |||||||
OR (95% CI) | P value | Global p Value | OR (95% CI) | P value | Global p Value | OR (95% CI) | P value | Global p Value | |
Gender | |||||||||
Male | Ref | ||||||||
Female | 1.03 (0.98, 1.08) | 0.244 | 0.98 (0.94, 1.03) | 0.539 | 1.08 (1.02, 1.14) | 0.008 | |||
Ethnicity | |||||||||
White | Ref | ||||||||
Non-white | 0.98 (0.91, 1.06) | 0.631 | 0.95 (0.88, 1.03) | 0.194 | 0.99 (0.91, 1.08) | 0.823 | |||
Age group (years) | |||||||||
15–49 | 0.94 (0.86, 1.03) | 0.181 | <0.001 | 0.87 (0.78, 0.96) | 0.005 | 0.022 | 1.30 (1.18, 1.43) | <0.001 | <0.001 |
50–59 | 0.97 (0.90, 1.04) | 0.383 | 0.93 (0.87, 1.00) | 0.066 | 1.03 (0.95, 1.12) | 0.434 | |||
60–69 | Ref | ||||||||
70–79 | 0.96 (0.90, 1.01) | 0.143 | 1.00 (0.95, 1.06) | 0.899 | 0.96 (0.90, 1.03) | 0.239 | |||
80+ | 0.85 (0.80, 0.91) | <0.001 | 0.97 (0.91, 1.03) | 0.325 | 0.78 (0.73, 0.84) | <0.001 | |||
Deprivation | |||||||||
1—least deprived | Ref | ||||||||
2 | 1.00 (0.93, 1.02) | 0.993 | 0.304 | 1.03 (0.96, 1.01) | 0.419 | 0.002 | 0.98 (0.91, 1.07) | 0.716 | 0.449 |
3 | 0.95 (0.89, 1.02) | 0.175 | 0.92 (0.86, 1.12) | 0.025 | 0.97 (0.89, 1.05) | 0.391 | |||
4 | 0.97 (0.91, 1.05) | 0.502 | 0.93 (0.87, 1.00) | 0.064 | 1.04 (0.96, 1.12) | 0.365 | |||
5—most deprived | 0.94 (0.87, 1.01) | 0.088 | 0.91 (0.84, 0.98) | 0.011 | 0.99 (0.92, 1.07) | 0.856 | |||
Morbidities | |||||||||
0 | Ref | ||||||||
1 | 0.85 (0.80, 0.91) | <0.001 | <0.001 | 0.86 (0.81, 0.92) | <0.001 | <0.001 | 0.92 (0.85, 0.98) | 0.012 | <0.001 |
2 | 0.77 (0.72, 0.83) | <0.001 | 0.81 (0.75, 0.86) | <0.001 | 0.85 (0.79, 0.92) | <0.001 | |||
3 | 0.72 (0.66, 0.77) | <0.001 | 0.76 (0.70, 0.82) | <0.001 | 0.79 (0.73, 0.86) | <0.001 | |||
4+ | 0.63 (0.58, 0.68) | <0.001 | 0.71 (0.65, 0.77) | <0.001 | 0.71 (0.64, 0.78) | <0.001 | |||
Cancer site | |||||||||
Bladder | 1.04 (0.91, 1.19) | 0.554 | <0.001 | 0.44 (0.38, 0.50) | <0.001 | <0.001 | 0.84 (0.71, 0.99) | 0.045 | <0.001 |
Brain | 0.20 (0.16, 0.24) | <0.001 | 0.18 (0.14, 0.22) | <0.001 | 0.60 (0.47, 0.78) | <0.001 | |||
Breast | 0.03 (0.02, 0.03) | <0.001 | 0.02 (0.02, 0.03) | <0.001 | 0.13 (0.11, 0.16) | <0.001 | |||
Cervical | 0.42 (0.33, 0.54) | <0.001 | 0.17 (0.13, 0.23) | <0.001 | 0.95 (0.68, 1.33) | 0.775 | |||
Colon | Ref | ||||||||
Endometrial | 0.43 (0.38, 0.49) | 0.489 | 0.21 (0.18, 0.24) | <0.001 | 1.87 (1.62, 2.17) | <0.001 | |||
Gallbladder | 1.13 (0.79, 1.62) | <0.001 | 0.88 (0.62, 1.23) | 0.445 | 3.35 (2.38, 4.72) | <0.001 | |||
Laryngeal | 0.36 (0.28, 0.45) | <0.001 | 0.16 (0.12, 0.21) | <0.001 | 2.17 (1.69, 2.78) | <0.001 | |||
Leukaemia | 1.50 (1.29, 1.74) | 0.029 | 1.70 (1.46, 1.96) | <0.001 | 0.72 (0.60, 0.87) | 0.001 | |||
Liver | 0.83 (0.71, 0.98) | 0.371 | 0.72 (0.61, 0.84) | <0.001 | 2.78 (2.34, 3.31) | 0.005 | |||
Lung | 0.96 (0.88, 1.05) | 0.015 | 0.30 (0.28, 0.33) | <0.001 | 6.31 (5.70, 6.98) | <0.001 | |||
Lymphoma | 0.87 (0.77, 0.97) | <0.001 | 0.60 (0.53, 0.67) | <0.001 | 2.54 (2.24, 2.88) | <0.001 | |||
Melanoma | 0.04 (0.04, 0.05) | 0.003 | 0.02 (0.01, 0.02) | <0.001 | 0.08 (0.06, 0.11) | <0.001 | |||
Mesothelioma | 1.42 (1.13, 1.79) | <0.001 | 0.37 (0.30, 0.46) | <0.001 | 10.61 (8.48, 13.27) | <0.001 | |||
Myeloma | 1.51 (1.27, 1.80) | <0.001 | 1.45 (1.22, 1.71) | <0.001 | 2.03 (1.70, 2.42) | 0.002 | |||
Oesophageal | 0.56 (0.49, 0.64) | <0.001 | 0.46 (0.40, 0.52) | <0.001 | 0.66 (0.55, 0.80) | <0.001 | |||
Oral | 0.18 (0.15, 0.20) | 0.035 | 0.14 (0.12, 0.16) | <0.001 | 0.81 (0.68, 0.98) | 0.035 | |||
Ovarian | 1.18 (1.01, 1.38) | 0.003 | 0.84 (0.73, 0.97) | 0.021 | 4.00 (3.43, 4.66) | <0.001 | |||
Pancreatic | 1.22 (1.07, 1.39) | <0.001 | 1.03 (0.91, 1.17) | 0.602 | 2.54 (2.10, 2.91) | <0.001 | |||
Prostate | 3.36 (3.04, 3.70) | <0.001 | 3.47 (3.16, 3.81) | <0.001 | 0.45 (0.40, 0.50) | <0.001 | |||
Rectal | 0.74 (0.66, 0.84) | <0.001 | 0.78 (0.69, 0.88) | <0.001 | 0.34 (0.27, 0.41) | <0.001 | |||
Renal | 0.73 (0.65, 0.83) | 0.821 | 0.37 (0.32, 0.42) | <0.001 | 2.59 (2.26, 2.97) | <0.001 | |||
Small intestine | 0.97 (0.73, 1.28) | 0.172 | 0.83 (0.63, 1.09) | 0.188 | 1.37 (1.00, 1.88) | 0.049 | |||
Stomach | 1.12 (0.95, 1.31) | 0.033 | 0.91 (0.78, 1.06) | 0.246 | 1.02 (0.84, 1.23) | 0.826 | |||
Testicular | 0.77 (0.61, 0.98) | 0.527 | 0.07 (0.05, 0.10) | <0.001 | 4.84 (3.83, 6.13) | <0.001 | |||
Thyroid | 1.07 (0.87, 1.30) | <0.001 | 0.47 (0.39, 0.57) | <0.001 | 4.26 (3.52, 5.16) | <0.001 | |||
Vulval | 0.09 (0.06, 0.14) | <0.001 | 0.05 (0.03, 0.09) | <0.001 | 0.26 (0.14, 0.50) | <0.001 | |||
Unknown primary | 0.77 (0.67, 0.90) | <0.001 | 0.59 (0.51, 0.68) | <0.001 | 2.51 (2.14, 2.95) | <0.001 | |||
Other | 0.45 (0.40, 0.50) | 0.489 | 0.31 (0.27, 0.34) | <0.001 | 1.47 (1.28, 1.67) | <0.001 |
Ref, reference.