Elsevier

The Lancet

Volume 347, Issue 9000, 24 February 1996, Pages 549-550
The Lancet

Letters to the Editor
Use of "off-label" and unlicensed drugs in paediatric intensive care unit

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References (4)

  • Am Gill et al.

    Adverse drug reactions in a paediatric intensive care unit

    Acta Paediatr

    (1995)
  • ABPI, ABPI data sheet compendium 1995-96, Datapharm Publications Ltd,...
There are more references available in the full text version of this article.

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    It remains ironic today that many drugs given to children are either not licensed for use in children at the dose, frequency or indication selected and are used in an off-label fashion, or are unlicensed (Choonara and Dunne, 1998). The fact that up to 40% of medicines given to children within the hospital setting are “unlicensed,” means that health care professionals who prescribe and administer such medicines must be extremely vigilant and fully aware of the consequences of their actions (Turner et al., 1996). Children are at great risk from the use of medicines for various reasons (Wong et al., 2009).

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