Patterns of antipsychotic utilization in a tertiary care psychiatric institution

Pharmacopsychiatry. 2004 Jan;37(1):12-7. doi: 10.1055/s-2004-815469.

Abstract

Objective: To perform a retrospective survey of discharge medications at a tertiary care psychiatric facility in an attempt to gain insight into, and perhaps an understanding of, the most recent pattern of antipsychotic utilization in patients with a diagnosis not restricted to schizophrenia.

Methods: This is a retrospective survey that used the Department of Pharmacy's computer database to obtain relevant discharge information on all non-geriatric patients discharged from Riverview Hospital between 1 January and 31 December 2000. The records of 372 patients met the inclusion criteria and formed the database for the survey.

Results: The results of this survey revealed a relatively high prevalence of antipsychotic polypharmacy (the use of two antipsychotics). Perhaps surprisingly, the highest rate of antipsychotic polypharmacy was found in individuals diagnosed with schizoaffective disorder (49.3%), followed by schizophrenia (44.7%), bipolar disorder (29.9%), and psychosis not otherwise specified (22.5%).

Conclusion: Although antipsychotic polypharmacy is not a new phenomenon in schizophrenia, this study is the first to document its employment among other diagnoses.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antipsychotic Agents / therapeutic use*
  • Bipolar Disorder / epidemiology
  • Bipolar Disorder / rehabilitation*
  • British Columbia
  • Chronic Disease
  • Dose-Response Relationship, Drug
  • Drug Therapy, Combination
  • Drug Utilization / statistics & numerical data
  • Female
  • Hospitals, Psychiatric / statistics & numerical data*
  • Hospitals, Teaching / statistics & numerical data
  • Humans
  • Male
  • Middle Aged
  • Patient Discharge / statistics & numerical data
  • Psychotic Disorders / epidemiology
  • Psychotic Disorders / rehabilitation*
  • Retrospective Studies
  • Schizophrenia / epidemiology
  • Schizophrenia / rehabilitation*

Substances

  • Antipsychotic Agents