Medication errors during medical emergencies in a large, tertiary care, academic medical center

Resuscitation. 2012 Apr;83(4):482-7. doi: 10.1016/j.resuscitation.2011.10.001. Epub 2011 Oct 14.

Abstract

Purpose: Evaluate the rate, type and severity of medication errors occurring during Medical Emergency Team (MET) care at a large, tertiary-care, academic medical center.

Methods: A prospective, observational evaluation of 50 patients that required MET care was conducted. Data on medication use were collected using a direct-observation method whereby an observer documented drug information such as drug, dose, frequency, rate of administration and administration technique. Subsequently, a team of three clinicians assessed rate, type and severity of medication errors using definitions consistent with United States Pharmacopeia MEDMARX system. Severity was assessed on a scale of minor, moderate and severe.

Results: One hundred eighty six doses were observed for 36 different medications. A total of 296 errors were identified; of these 196 errors (66%) were inappropriate aseptic technique. Of the remaining 100 errors, 46% were prescribing errors, 28% administration technique errors, 14% mislabeling errors, 10% drug preparation errors and 2% improper dose prescribing. Examples included: (1) prescribing errors, (2) administering wrong doses, (3) mislabeling, and (4) wrong administration technique such as not flushing intravenous medication through intravenous access. The rate of medication administration errors was 1.6 errors/dose including aseptic technique and 0.5 errors/dose excluding aseptic technique. A notable portion (14%) of errors was considered at least moderate in severity.

Conclusions: One out of 2 doses was administered in error after errors of using inappropriate aseptic technique were excluded. There is a need for education and systematic changes to prevent medication errors during medical emergencies as an effort to avoid harm.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Academic Medical Centers
  • Adult
  • Aged
  • Cohort Studies
  • Dose-Response Relationship, Drug
  • Drug-Related Side Effects and Adverse Reactions*
  • Emergencies
  • Emergency Service, Hospital
  • Female
  • Hospital Mortality / trends*
  • Humans
  • Incidence
  • Male
  • Medication Errors / prevention & control
  • Medication Errors / statistics & numerical data*
  • Medication Systems, Hospital / standards*
  • Medication Systems, Hospital / trends
  • Middle Aged
  • Needs Assessment
  • Patient Care Team
  • Prospective Studies
  • Risk Assessment
  • Safety Management
  • Survival Rate
  • United States
  • Urban Population