Historically, insomnia has been viewed as a symptom of depressive illness that is expected
to resolve with adequate treatment of the depressive disorder. This article reviews the …

NK cell infiltration into solid tumors is often low and is largely represented by the poorly-
cytotoxic CD56bright subset. Numerous studies have demonstrated that CD73 …

Energy metabolism is key to the promotion of tumor growth, development, and metastasis. At
the same time, cellular metabolism also mediates immune cell survival, proliferation and …

This paper focuses on pragmatic issues in obtaining measures of cardiac vagal control, and
overviews a set of freely available software tools for obtaining several widely used metrics …

The aim of CALL practitioners is to work towards a state where computers are fully
integrated into pedagogy, a state of 'normalisation'. This article draws on a qualitative …

Background Because of the paucity of effective evidence-based therapies for children with
recurrent abdominal pain, we evaluated the therapeutic effect of guided imagery, a well …

Increased vagal tone has been associated with treatment success using pharmacological
agents and cognitive-behavioral treatment in major depression, but not using …

OBJECTIVE: To estimate the efficacy of acupuncture for depression during pregnancy in a
randomized controlled trial. METHODS: A total of 150 pregnant women who met Diagnostic …

Background The anti-tumor immunity of natural killer (NK) cells can be paralyzed by the
CD73-induced generation of immunosuppressive adenosine from precursor ATP within the …

Adenosine is a potent immunosuppressive purine metabolite contributing to the
pathogenesis of solid tumors. Extracellular adenosine signals on tumor-infiltrating NK cells …