The geometry and dimensions of branched structures such as blood vessels or airways are
important factors in determining the efficiency of physiological processes. It has been shown …

The molecular nature of calcium (Ca 2+)-dependent mechanisms and the ion channels
having a major role in the apoptosis of cancer cells remain a subject of debate. Here, we …

One major clinical problem with prostate cancer is the cells' ability to survive and proliferate
upon androgen withdrawal. Because Ca2+ is central to growth control, understanding the …

In recent years, the transient receptor potential melastatin member 8 (TRPM8) channel has
emerged as a promising prognostic marker and putative therapeutic target in prostate …

Accumulating data point to K+ channels as relevant players in controlling cell cycle
progression and proliferation of human cancer cells, including prostate cancer (PCa) cells …

Antiapoptotic oncoprotein Bcl-2 has extramitochondrial actions due to its localization on the
endoplasmic reticulum (ER); however, the specific mechanisms of such actions remain …

Neuroendocrine (NE) differentiation is a hallmark of advanced, androgen-independent
prostate cancer, for which there is no successful therapy. NE tumor cells are nonproliferating …

The progress in the surgery of male neurological cancers relies on the anatomico-surgical
approach to the pelvic neural structures. The objective of our study was to provide a better …

TRPM8 (melastatine-related transient receptor potential member 8), a member of the
transient receptor potential (TRP) superfamily of cation channels, has been shown to be a …

The aim of this study was to provide quantitative data on the origin and trajectory of the main
renal arteries using spiral CT angiography and arteriography. Normal renal artery anatomy …