Objectives To assess the overall effect of vitamin D supplementation on risk of acute
respiratory tract infection, and to identify factors modifying this effect. Design Systematic …

Psoriasis, a papulosquamous skin disease, was originally thought of as a disorder primarily
of epidermal keratinocytes, but is now recognised as one of the commonest immune …

The worldwide incidence and prevalence of psoriasis is poorly understood. To better
understand this, we performed a systematic review of published population-based studies …

Zebrafish have become a popular organism for the study of vertebrate gene function,. The
virtually transparent embryos of this species, and the ability to accelerate genetic studies by …

The murine monoclonal antibody OC 125 reacts with an antigen (CA 125) common to most
nonmucinous epithelial ovarian carcinomas. An assay has been developed to detect CA …

Introduction In the real-world APPRECIATE study (NCT02740218), most patients with
psoriasis demonstrated notable improvements on disease severity measures and reported …

The human X chromosome has a unique biology that was shaped by its evolution as the sex
chromosome shared by males and females. We have determined 99.3% of the euchromatic …

Background Interleukin-17A is considered to be central to the pathogenesis of psoriasis. We
evaluated secukinumab, a fully human anti–interleukin-17A monoclonal antibody, in …

European S3-Guidelines on the systemic treatment of psoriasis vulgaris D Pathirana, AD
Ormerod, P Saiag, C Smith, PI Spuls, A Na Page 1 JEADV october 2009, volume 23 …

Patients with moderate to severe psoriasis are undertreated. To solve this persistent
problem, the consensus programme was performed to define goals for treatment of plaque …