The pyrogenic property being the first activity described, members of the interleukin-1
superfamily (IL-1α, IL-1β, IL-18, and the newest members: IL-33, IL-36, IL-37, and IL-38) are …

Background Sorafenib is the recommended treatment for patients with advanced
hepatocellular carcinoma. We aimed to compare the efficacy and safety of sorafenib to that …

Background & Aims We performed a prospective study to investigate the effects of a
sustained viral response (SVR) on outcomes of patients with hepatitis C virus (HCV) …

Background Patients with primary biliary cholangitis who have an inadequate response to
therapy with ursodeoxycholic acid are at high risk for disease progression. Fibrates, which …

IgG4-related systemic disease is now recognized as a systemic disease that may affect
various organs. The diagnosis is usually made in patients who present with elevated IgG4 in …

Importance Prednisolone or pentoxifylline is recommended for severe alcoholic hepatitis, a
life-threatening disease. The benefit of their combination is unknown. Objective To …

Background Early liver transplantation for severe alcohol-related hepatitis is an emerging
treatment option. We aimed to assess the risk of alcohol relapse 2 years after early liver …

Background & Aims Retrospective studies have found an unexpectedly high incidence of
hepatocellular carcinoma (HCC) among patients with hepatitis C virus (HCV)-associated …

Background In patients with cirrhosis, pharmacologic or endoscopic treatment may control
variceal bleeding. However, the effects of early administration of a somatostatin analogue …

Background Sclerotherapy is considered the most effective way to stop bleeding from
esophageal varices, but acute variceal bleeding is still associated with a high risk of …