Objective: To evaluate efficacy of probiotics in prevention and treatment of diarrhoea
associated with the use of antibiotics. Design: Meta-analysis; outcome data (proportion of …

Older patients are particularly vulnerable to adverse drug reactions (ADRs) because age is
associated with changes in pharmacokinetics and pharmacodynamics that may alter drug …

Importance Hypertension treatment is beneficial for most hypertensive patients. The benefits
for patients who are very old and frail, especially those taking numerous medications, are …

Background Whether the treatment of patients with hypertension who are 80 years of age or
older is beneficial is unclear. It has been suggested that antihypertensive therapy may …

Objective To determine the efficacy of a probiotic drink containing Lactobacillus for the
prevention of any diarrhoea associated with antibiotic use and that caused by Clostridium …

Background The aim of the present study was to develop and validate a method of
identifying elderly patients who are at increased risk for an adverse drug reaction (ADR) …

Objectives. This study investigated the effects of hormonal therapy on large arterial
properties. Background. Arterial stiffness is an emerging risk marker for coronary heart …

The role of androgens in cardiovascular disease is uncertain. We aimed to determine the
vascular effects of androgen suppression in men with prostate cancer. Arterial stiffness (or …

Aortic stiffness and chronic kidney disease are closely linked by shared risk factors and
associated increased cardiovascular mortality. At lower levels of renal function, aortic …

Medial arterial calcification is accelerated in patients with CKD and strongly associated with
increased arterial rigidity and cardiovascular mortality. Recently, a novel in vitro blood test …